Gene: elav - Drosophila melanogaster
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Gene Symbol | : | elav | ||||||||||||
NCBI Gene ID | : | 31000 | ||||||||||||
Species | : | Drosophila melanogaster | ||||||||||||
Gene Synonyms | : | 44C11 | 9F8A9 | CG4262 | CG4262-PA | CG4262-PB | CG4262-PC | CG4262-PD | Dmel_CG4262 | DmelCG4262 | EC7 | ELAV | ElaV | Elav | elav | elav-1 | elav-2 | elav-3 | Elav-9F8A9 | elav-PA | elav-PB | elav-PC | elav-PD | Embryonic Lethal Abnormal Vision | Embryonic lethal abnormal vision | embryonic lethal abnormal vision | Embryonic lethal abnormal visual system | embryonic lethal abnormal visual system | embryonic lethal, abnormal vision | fliJ | l(1)1Be | l(1)EC7 | l(1)G0031 | l(1)G0319 | weg | weniger Source: GPSDB |
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Gene Homologs | : | |||||||||||||
Ageing Relevance Analysis | : |
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Ageing Factor Stable ID | : | AF_000020 | ||||||||||||
Download | : | XML |
Protein Information
Protein Name | Species | UniProt Accession Number | UniProt Entry Name | Protein Function | Sequence |
---|---|---|---|---|---|
Protein elav | Drosophila melanogaster | P16914 (UniProtKB/Swiss-Prot) | ELAV_DROME (UniProtKB/Swiss-Prot) | Required for the proper development and maintenance of neurons presumably by affecting RNA metabolism. | View |
Observations
Ageing Phenotype
Data Type 1
no ageing phenotype observation—data type 1 available
Data Type 2
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Organism | Ageing Factor | Lifespan Observation | Reference | ||||||||||||||||||||||||||||||||
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# | Observation Stable ID | Species | Strain | Gene | Compound | Other Ageing Factor | Significant Lifespan Effect | Change | Observed Lifespan | Reference Lifespan | Lifespan Unit | Measure | Temperature | Temperature Unit | Sex/Mating Type | Description | Author | Year | PubMed | DOI | Source | ||||||||||||||
1 | OB_006355 | Drosophila melanogaster |
|
decreased | -66.00% | unknown | male | Longevity was significantly decreased in elav mutants compared with the control. | Toba et al. | 2010 | 20589912 | doi:10.1002/arch.20377 | GenAge |
Homology Analysis
no homology analysis observation available
Sequences
ELAV_DROME | P16914 | Protein elav (Drosophila melanogaster) from UniProtKB/Swiss-Prot Length: 483 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 ELAV_DROME 1 MDFIMANTGAGGGVDTQAQLMQSAAAAAAVAATNAAAAPVQNAAAVAAAAQLQQQQVQQAILQVQQQQTQQAVAAAAAAVTQQLQQQQQAVVAQQAVVQQQQQQAAAVVQQAAVQQAVVPQPQQAQPNTNGNAGSGSQNGSNGSTETRTNLIVNYLPQTMTEDEIRSLFSSVGEIESVKLIRDKSQVYIDPLNPQAPSKGQSLGYGFVNYVRPQDAEQAVNVLNGLRLQNKTIKVSFARPSSDAIKGANLYVSGLPKTMTQQELEAIFAPFGAIITSRILQNAGNDTQTKGVGFIRFDKREEATRAIIALNGTTPSSCTDPIVVKFSNTPGSTSKIIQPQLPAFLNPQLVRRIGGAMHTPVNKGLARFSPMAGDMLDVMLPNGLGAAAAAATTLASGPGGAYPIFIYNLAPETEEAALWQLFGPFGAVQSVKIVKDPTTNQCKGYGFVSMTNYDEAAMAIRALNGYTMGNRVLQVSFKTNKAK 483
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Toba G, Yamamoto D, White K:
Life-span phenotypes of elav and Rbp9 in Drosophila suggest functional cooperation of the two ELAV-family protein genes.
Arch Insect Biochem Physiol. 2010; 74: 261-5.
PubMed (ID: 20589912), doi:10.1002/arch.20377
MeSH Terms: Drosophila Proteins/physiology; Drosophila/genetics; Hu Paraneoplastic Encephalomyelitis Antigens/physiology; Nerve Tissue Proteins/physiology; RNA-Binding Proteins/physiology
Sources
Ageing-related Data Sources
Additional Data Sources
- AgeFactDB Pipeline
- GPSDB
- NCBI Taxonomy
- PubMed
- UniProtKB/Swiss-Prot