Gene: Htr1b - Rattus norvegicus
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Gene Symbol | : | Htr1b | ||||||||||||
NCBI Gene ID | : | 25075 | ||||||||||||
Species | : | Rattus norvegicus | ||||||||||||
Gene Synonyms | : | 5-HT-1B | 5-HT1B serotonin receptor | 5-hydroxytryptamine (serotonin ) receptor 1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled | 5-hydroxytryptamine receptor 1B | 5ht1b | Htr1b | serotonin (5-hydroxytryptamine (5HT)) receptor type 1B | serotonin receptor 1B Source: GPSDB |
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Gene Homologs | : | 5-HT7 (Drosophila melanogaster) | GPR5HT7 (Anopheles gambiae) | GPRNNA20 (Anopheles gambiae) | HTR1B (Bos taurus) | HTR1B (Canis lupus familiaris) | htr1b (Danio rerio) | HTR1B (Gallus gallus) | HTR1B (Homo sapiens) | HTR1B (Macaca mulatta) | htr1b (Mus musculus) | HTR1B (Pan troglodytes) | Htr1b (Rattus norvegicus) | ||||||||||||
Ageing Relevance Analysis | : |
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Ageing Factor Stable ID | : | AF_000044 | ||||||||||||
Download | : | XML |
Protein Information
Protein Name | Species | UniProt Accession Number | UniProt Entry Name | Protein Function | Sequence |
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5-hydroxytryptamine receptor 1B | Rattus norvegicus | P28564 (UniProtKB/Swiss-Prot) | 5HT1B_RAT (UniProtKB/Swiss-Prot) | This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. | View |
Observations
Ageing Phenotype
Data Type 1
no ageing phenotype observation—data type 1 available
Data Type 2
no ageing phenotype observation—data type 2 available
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:
- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
# | Observation Stable ID | Homology Group Genes | #EGHG | Description | Source | Homology Source |
---|---|---|---|---|---|---|
1 | OB_008921 | 1 | The HomoloGene homology group 669 contains 1 gene with experimental evidence for ageing relevance (Htr1b - Mus musculus) and 11 other genes. | AgeFactDB Homology Analysis | HomoloGene homology group 669 |
Sequences
5HT1B_RAT | P28564 | 5-hydroxytryptamine receptor 1B (Rattus norvegicus) from UniProtKB/Swiss-Prot Length: 386 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 5HT1B_RAT 1 MEEQGIQCAPPPPATSQTGVPLANLSHNCSADDYIYQDSIALPWKVLLVALLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIMHLCVIALDRYWAITDAVDYSAKRTPKRAAIMIVLVWVFSISISLPPFFWRQAKAEEEVLDCFVNTDHVLYTVYSTVGAFYLPTLLLIALYGRIYVEARSRILKQTPNKTGKRLTRAQLITDSPGSTSSVTSINSRVPEVPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFNWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTG 386
References
no reference information available
Sources
Ageing-related Data Sources
- AgeFactDB Homology Analysis
Additional Data Sources
- AgeFactDB Pipeline
- GPSDB
- HomoloGene
- UniProtKB/Swiss-Prot