Gene: VPS34 - Saccharomyces cerevisiae
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Gene Symbol | : | VPS34 | ||||||||||||||||
NCBI Gene ID | : | 850941 | ||||||||||||||||
Species | : | Saccharomyces cerevisiae | ||||||||||||||||
Gene Synonyms | : | END12 | L9672.10 | PEP15 | phosphatidylinositol 3-kinase VPS34 | STT8 | VPL7 | VPS34 | Vps34p | VPS7 | VPT29 | YLR240W Source: GPSDB |
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Gene Homologs | : | AgaP_AGAP010273 (Anopheles gambiae) | AGOS_AGL113C (Eremothecium gossypii) | AT1G60490.1 (Arabidopsis thaliana) | KLLA0D18645g (Kluyveromyces lactis) | LOC100857877 (Gallus gallus) | MGG_03069 (Magnaporthe oryzae) | NCU00656 (Neurospora crassa) | Os05g0180600 (Oryza sativa) | Pi3K59F (Drosophila melanogaster) | pik3 (Schizosaccharomyces pombe) | PIK3C3 (Bos taurus) | PIK3C3 (Canis lupus familiaris) | pik3c3 (Danio rerio) | PIK3C3 (Homo sapiens) | PIK3C3 (Macaca mulatta) | Pik3c3 (Mus musculus) | PIK3C3 (Pan troglodytes) | Pik3c3 (Rattus norvegicus) | vps-34 (Caenorhabditis elegans) | VPS34 (Saccharomyces cerevisiae) | ||||||||||||||||
Ageing Relevance Analysis | : |
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Ageing Factor Stable ID | : | AF_000112 | ||||||||||||||||
Download | : | XML |
Protein Information
no protein information available
Observations
Ageing Phenotype
Data Type 1
no ageing phenotype observation—data type 1 available
Data Type 2
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Organism | Ageing Factor | Lifespan Observation | Reference | ||||||||||||||||||||||||||||||||
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# | Observation Stable ID | Species | Strain | Gene | Compound | Other Ageing Factor | Significant Lifespan Effect | Change | Observed Lifespan | Reference Lifespan | Lifespan Unit | Measure | Temperature | Temperature Unit | Sex/Mating Type | Description | Author | Year | PubMed | DOI | Source | ||||||||||||||
1 | OB_007524 | Saccharomyces cerevisiae |
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decreased | -60.00% | unknown | Replicative lifespan decreased by 60% in the a strain | Smith et al. | 2008 | 18340043 | doi:10.1101/gr.074724.107 | GenAge |
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:
- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
Sequences
no sequence information available
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Smith ED, Tsuchiya M, Fox LA, Dang N, Hu D, Kerr EO, Johnston ED, Tchao BN, Pak DN, Welton KL, Promislow DE, Thomas JH, Kaeberlein M, Kennedy BK:
Quantitative evidence for conserved longevity pathways between divergent eukaryotic species.
Genome Res. 2008; 18: 564-70.
PubMed (ID: 18340043), PubMed Central (ID: PMC2279244), doi:10.1101/gr.074724.107
MeSH Terms: Caenorhabditis elegans/genetics; Longevity/genetics; Saccharomyces cerevisiae/genetics
Sources
Ageing-related Data Sources
- AgeFactDB Homology Analysis
- GenAge
Additional Data Sources
- AgeFactDB Pipeline
- GPSDB
- HomoloGene
- NCBI Taxonomy
- PubMed