Gene: Gclm - Mus musculus
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Gene Symbol | : | Gclm | ||||||||||||
NCBI Gene ID | : | 14630 | ||||||||||||
Species | : | Mus musculus | ||||||||||||
Gene Synonyms | : | gamma-ECS regulatory subunit | gamma-glutamylcysteine synthetase regulatory subunit | Gclm | Gcmc | GCS light chain | Glclr | glutamate cysteine ligase (gamma-glutamylcysteine synthetase), regulatory | glutamate--cysteine ligase modifier subunit | glutamate--cysteine ligase regulatory subunit | glutamate-cysteine ligase, modifier subunit Source: GPSDB |
||||||||||||
Gene Homologs | : | AgaP_AGAP012038 (Anopheles gambiae) | E01A2.1 (Caenorhabditis elegans) | GCLM (Bos taurus) | GCLM (Canis lupus familiaris) | gclm (Danio rerio) | Gclm (Drosophila melanogaster) | GCLM (Gallus gallus) | GCLM (Homo sapiens) | Gclm (Mus musculus) | GCLM (Pan troglodytes) | Gclm (Rattus norvegicus) | ||||||||||||
Ageing Relevance Analysis | : |
|
||||||||||||
Ageing Factor Stable ID | : | AF_000386 | ||||||||||||
Download | : | XML |
Protein Information
Protein Name | Species | UniProt Accession Number | UniProt Entry Name | Protein Function | Sequence |
---|---|---|---|---|---|
Glutamate--cysteine ligase regulatory subunit | Mus musculus | O09172 (UniProtKB/Swiss-Prot) | GSH0_MOUSE (UniProtKB/Swiss-Prot) | View | |
Gclm protein | Mus musculus | Q4FJZ6 (UniProtKB/TrEMBL) | Q4FJZ6_MOUSE (UniProtKB/TrEMBL) | View |
Observations
Ageing Phenotype
Data Type 1
no ageing phenotype observation—data type 1 available
Data Type 2
no ageing phenotype observation—data type 2 available
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:
- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
# | Observation Stable ID | Homology Group Genes | #EGHG | Description | Source | Homology Source |
---|---|---|---|---|---|---|
1 | OB_008210 | 2 | The HomoloGene homology group 1557 contains 2 genes with experimental evidence for ageing relevance (GCLM - Homo sapiens | Gclm - Drosophila melanogaster) and 9 other genes. | AgeFactDB Homology Analysis | HomoloGene homology group 1557 |
Sequences
GSH0_MOUSE | O09172 | Glutamate--cysteine ligase regulatory subunit (Mus musculus) from UniProtKB/Swiss-Prot Length: 274 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 GSH0_MOUSE 1 MGTDSRAAGALLARASTLHLQTGNLLNWGRLRKKCPSTHSEELRDCIQKTLNEWSSQISPDLVREFPDVLECTMSHAVEKINPDEREEMKVSAKLFIVGSNSSSSTRSAVDMACSVLGVAQLDSVIMASPPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHNDPKELLSEASFQEALQESIPDIEAQDWVPLWLLRYSVIVKSRGIIKSKGYILQAKRRGS 274
Q4FJZ6_MOUSE | Q4FJZ6 | Gclm protein (Mus musculus) from UniProtKB/TrEMBL Length: 274 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 Q4FJZ6_MOUSE 1 MGTDSRAAGALLARASTLHLQTGNLLNWGRLRKKCPSTHSEELRDCIQKTLNEWSSQISPDLVREFPDVLECTMSHAVEKINPDEREEMKVSAKLFIVGSNSSSSTRSAVDMACSVLGVAQLDSVIMASPPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHNDPKELLSEASFQEALQESIPDIEAQDWVPLWLLRYSVIVKSRGIIKSKGYILQAKRRGS 274
References
no reference information available
Sources
Ageing-related Data Sources
- AgeFactDB Homology Analysis
Additional Data Sources
- AgeFactDB Pipeline
- GPSDB
- HomoloGene
- UniProtKB/Swiss-Prot
- UniProtKB/TrEMBL