Gene: HSC82 - Saccharomyces cerevisiae
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Gene Symbol | : | HSC82 | ||||||||||||||||||||
NCBI Gene ID | : | 855224 | ||||||||||||||||||||
Species | : | Saccharomyces cerevisiae | ||||||||||||||||||||
Gene Synonyms | : | HSC82 | Hsc82p | HSP90 | Hsp90 family chaperone HSC82 | YM8010.16 | YMR186W Source: GPSDB |
||||||||||||||||||||
Gene Homologs | : | AGOS_AFL148C (Eremothecium gossypii) | HSC82 (Saccharomyces cerevisiae) | HSP82 (Saccharomyces cerevisiae) | HSP90-1 (Arabidopsis thaliana) | HSP90AA1 (Bos taurus) | HSP90AA1 (Canis lupus familiaris) | HSP90AA1 (Gallus gallus) | HSP90AA1 (Homo sapiens) | HSP90AA1 (Macaca mulatta) | Hsp90aa1 (Mus musculus) | HSP90AA1 (Pan troglodytes) | Hsp90aa1 (Rattus norvegicus) | hsp90aa1.2 (Danio rerio) | KLLA0D12958g (Kluyveromyces lactis) | MGG_06759 (Magnaporthe oryzae) | NCU04142 (Neurospora crassa) | swo1 (Schizosaccharomyces pombe) | ||||||||||||||||||||
Ageing Relevance Analysis | : |
|
||||||||||||||||||||
Ageing Factor Stable ID | : | AF_000651 | ||||||||||||||||||||
Download | : | XML |
Protein Information
no protein information available
Observations
Ageing Phenotype
Data Type 1
no ageing phenotype observation—data type 1 available
Data Type 2
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Organism | Ageing Factor | Lifespan Observation | Reference | ||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
# | Observation Stable ID | Species | Strain | Gene | Compound | Other Ageing Factor | Significant Lifespan Effect | Change | Observed Lifespan | Reference Lifespan | Lifespan Unit | Measure | Temperature | Temperature Unit | Sex/Mating Type | Description | Author | Year | PubMed | DOI | Source | ||||||||||||||
1 | OB_004149 | Saccharomyces cerevisiae | BY4742 |
|
decreased | -17.00% | 30.4 | mean | 30 | ℃ | The hsc82 deletion from the MATalpha haploid yeast orf deletion collection had a shortened replicative life span relative to wild type BY4742 cells. | Kaeberlein et al. | 2005 | 15722108 | doi:10.1016/j.mad.2004.10.007 | Lifespan Observations Database (ID: 841) |
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:
- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
# | Observation Stable ID | Homology Group Genes | #EGHG | Description | Source | Homology Source |
---|---|---|---|---|---|---|
1 | OB_009022 | 2 | The HomoloGene homology group 68464 contains 2 genes with experimental evidence for ageing relevance (HSC82 - Saccharomyces cerevisiae | HSP90AA1 - Homo sapiens) and 15 other genes. | AgeFactDB Homology Analysis | HomoloGene homology group 68464 |
Sequences
no sequence information available
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Kaeberlein M, Kirkland KT, Fields S, Kennedy BK:
Genes determining yeast replicative life span in a long-lived genetic background.
Mech Ageing Dev. 2005; 126: 491-504.
PubMed (ID: 15722108), doi:10.1016/j.mad.2004.10.007
MeSH Terms: Cell Aging/genetics; Gene Expression Regulation, Fungal/genetics; Saccharomyces cerevisiae Proteins/genetics; Saccharomyces cerevisiae/genetics
Sources
Ageing-related Data Sources
- AgeFactDB Curator
- AgeFactDB Homology Analysis
- Lifespan Observations Database
Additional Data Sources
- AgeFactDB Pipeline
- GPSDB
- HomoloGene
- NCBI Taxonomy
- PubMed