Gene: IDH2 - Saccharomyces cerevisiae
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Gene Symbol |
: |
IDH2 |
NCBI Gene ID |
: |
854303 |
Species |
: |
Saccharomyces cerevisiae |
Gene Synonyms |
: |
IDH2 | Idh2p | isocitrate dehydrogenase (NAD(+)) IDH2 | O3326 | YOR136W | YOR3326W
Source: GPSDB |
Gene Homologs |
: |
AgaP_AGAP002728 (Anopheles gambiae) | AGOS_AFR137C (Eremothecium gossypii) | F43G9.1 (Caenorhabditis elegans) | IDH2 (Saccharomyces cerevisiae) | idh2 (Schizosaccharomyces pombe) | IDH3A (Bos taurus) | IDH3A (Canis lupus familiaris) | idh3a (Danio rerio) | IDH3A (Gallus gallus) | IDH3A (Homo sapiens) | IDH3A (Macaca mulatta) | Idh3a (Mus musculus) | IDH3A (Pan troglodytes) | Idh3a (Rattus norvegicus) | IDH5 (Arabidopsis thaliana) | IDH6 (Arabidopsis thaliana) | KLLA0E03125g (Kluyveromyces lactis) | l(1)G0156 (Drosophila melanogaster) | MGG_01712 (Magnaporthe oryzae) | NCU07697 (Neurospora crassa) | Os01g0276100 (Oryza sativa) |
Ageing Relevance Analysis |
: |
Observation Type |
Count |
Ageing Relevance |
Source |
Ageing Phenotype Observation—Data Type 1 |
1 |
yes (Exp. Analysis) |
GenDR |
Ageing Phenotype Observation—Data Type 2 Lifespan Effect |
|
|
|
increased |
1 |
yes (Exp. Analysis) |
Lifespan Observations Database |
Homology Analysis |
1 |
- (basis for a Comp. Analysis) putative (Comp. Analysis) |
AgeFactDB Homology Analysis |
Total |
3 |
|
|
|
Ageing Factor Stable ID |
: |
AF_000742 |
Download |
: |
XML |
Protein Information
no protein information available
Observations
Ageing Phenotype
Data Type 1
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Data Type 2
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
# |
Observation Stable ID |
Homology Group Genes |
#EGHG |
Description |
Source |
Homology Source |
1 |
OB_009133 |
|
2 |
The HomoloGene homology group 4037 contains 2 genes with experimental evidence for ageing relevance (IDH2 - Saccharomyces cerevisiae | idha-1 - Caenorhabditis elegans) and 19 other genes. |
AgeFactDB Homology Analysis |
HomoloGene homology group 4037 |
Sequences
no sequence information available
References
MeSH Terms:
Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms.
They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page.
MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Kaeberlein M, Powers RW, Steffen KK, Westman EA, Hu D, Dang N, Kerr EO, Kirkland KT, Fields S, Kennedy BK:
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients.
Science. 2005; 310: 1193-6.
PubMed (ID: 16293764), doi:10.1126/science.1115535
MeSH Terms: Protein Kinases/metabolism; Saccharomyces cerevisiae Proteins/physiology; Saccharomyces cerevisiae/physiology
- Smith ED, Tsuchiya M, Fox LA, Dang N, Hu D, Kerr EO, Johnston ED, Tchao BN, Pak DN, Welton KL, Promislow DE, Thomas JH, Kaeberlein M, Kennedy BK:
Quantitative evidence for conserved longevity pathways between divergent eukaryotic species.
Genome Res. 2008; 18: 564-70.
PubMed (ID: 18340043), PubMed Central (ID: PMC2279244), doi:10.1101/gr.074724.107
MeSH Terms: Caenorhabditis elegans/genetics; Longevity/genetics; Saccharomyces cerevisiae/genetics
- Managbanag JR, Witten TM, Bonchev D, Fox LA, Tsuchiya M, Kennedy BK, Kaeberlein M:
Shortest-path network analysis is a useful approach toward identifying genetic determinants of longevity.
PLoS ONE. 2008; 3: e3802.
PubMed (ID: 19030232), PubMed Central (ID: PMC2583956), doi:10.1371/journal.pone.0003802
MeSH Terms: Cell Physiological Phenomena/genetics; Gene Regulatory Networks; Saccharomyces cerevisiae/cytology; Saccharomyces cerevisiae/genetics
Sources
Ageing-related Data Sources
Additional Data Sources