Gene: MTC1 - Saccharomyces cerevisiae
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Gene Symbol | : | MTC1 | ||||||||||||||||
NCBI Gene ID | : | 853319 | ||||||||||||||||
Species | : | Saccharomyces cerevisiae | ||||||||||||||||
Gene Synonyms | : | J0718 | MTC1 | Mtc1p | YJL123C Source: GPSDB |
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Gene Homologs | : | AGOS_AFL210C (Eremothecium gossypii) | KLLA0E15115g (Kluyveromyces lactis) | MGG_04924 (Magnaporthe oryzae) | MTC1 (Saccharomyces cerevisiae) | NCU02899 (Neurospora crassa) | SPCC1322.09 (Schizosaccharomyces pombe) | ||||||||||||||||
Ageing Relevance Analysis | : |
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Ageing Factor Stable ID | : | AF_000838 | ||||||||||||||||
Download | : | XML |
Protein Information
no protein information available
Observations
Ageing Phenotype
Data Type 1
no ageing phenotype observation—data type 1 available
Data Type 2
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Organism | Ageing Factor | Lifespan Observation | Reference | ||||||||||||||||||||||||||||||||
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# | Observation Stable ID | Species | Strain | Gene | Compound | Other Ageing Factor | Significant Lifespan Effect | Change | Observed Lifespan | Reference Lifespan | Lifespan Unit | Measure | Temperature | Temperature Unit | Sex/Mating Type | Description | Author | Year | PubMed | DOI | Source | ||||||||||||||
1 | OB_007776 | Saccharomyces cerevisiae |
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decreased | unknown | Mean replicative lifespan decreased in the alpha and a strain | Fabrizio et al. | 2010 | 20657825 | doi:10.1371/journal.pgen.1001024 | GenAge |
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:
- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
# | Observation Stable ID | Homology Group Genes | #EGHG | Description | Source | Homology Source |
---|---|---|---|---|---|---|
1 | OB_008175 | 1 | The HomoloGene homology group 6231 contains 1 gene with experimental evidence for ageing relevance (MTC1 - Saccharomyces cerevisiae) and 5 other genes. | AgeFactDB Homology Analysis | HomoloGene homology group 6231 |
Sequences
no sequence information available
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Fabrizio P, Hoon S, Shamalnasab M, Galbani A, Wei M, Giaever G, Nislow C, Longo VD:
Genome-wide screen in Saccharomyces cerevisiae identifies vacuolar protein sorting, autophagy, biosynthetic, and tRNA methylation genes involved in life span regulation.
PLoS Genet. 2010; 6: e1001024.
PubMed (ID: 20657825), PubMed Central (ID: PMC2904796), doi:10.1371/journal.pgen.1001024
MeSH Terms: Genome, Fungal; Longevity/genetics; Saccharomyces cerevisiae/genetics
Sources
Ageing-related Data Sources
- AgeFactDB Homology Analysis
- GenAge
Additional Data Sources
- AgeFactDB Pipeline
- GPSDB
- HomoloGene
- NCBI Taxonomy
- PubMed