Gene: RPL6A - Saccharomyces cerevisiae
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Gene Symbol | : | RPL6A | ||||||||||||||||||||||||
NCBI Gene ID | : | 854902 | ||||||||||||||||||||||||
Species | : | Saccharomyces cerevisiae | ||||||||||||||||||||||||
Gene Synonyms | : | L17A | L6A | L6e | ribosomal 60S subunit protein L6A | rp18 | RPL17A | RPL6A | Rpl6ap | YL16 | YL16A | YML073C Source: GPSDB |
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Gene Homologs | : | AgaP_AGAP001911 (Anopheles gambiae) | AGOS_AER149W (Eremothecium gossypii) | Gm5428 (Mus musculus) | KLLA0B04686g (Kluyveromyces lactis) | LOC712820 (Macaca mulatta) | LOC737972 (Pan troglodytes) | MGG_04444 (Magnaporthe oryzae) | NCU02707 (Neurospora crassa) | Os02g0591700 (Oryza sativa) | Os04g0473400 (Oryza sativa) | rpl-6 (Caenorhabditis elegans) | RPL6 (Bos taurus) | RPL6 (Canis lupus familiaris) | rpl6 (Danio rerio) | RpL6 (Drosophila melanogaster) | RPL6 (Gallus gallus) | RPL6 (Homo sapiens) | RPL6 (Macaca mulatta) | Rpl6 (Mus musculus) | Rpl6 (Rattus norvegicus) | rpl6 (Schizosaccharomyces pombe) | RPL6A (Arabidopsis thaliana) | RPL6A (Saccharomyces cerevisiae) | RPL6B (Arabidopsis thaliana) | RPL6B (Saccharomyces cerevisiae) | RPL6C (Arabidopsis thaliana) | ||||||||||||||||||||||||
Ageing Relevance Analysis | : |
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Ageing Factor Stable ID | : | AF_000967 | ||||||||||||||||||||||||
Download | : | XML |
Protein Information
no protein information available
Observations
Ageing Phenotype
Data Type 1
no ageing phenotype observation—data type 1 available
Data Type 2
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Organism | Ageing Factor | Lifespan Observation | Reference | ||||||||||||||||||||||||||||||||
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# | Observation Stable ID | Species | Strain | Gene | Compound | Other Ageing Factor | Significant Lifespan Effect | Change | Observed Lifespan | Reference Lifespan | Lifespan Unit | Measure | Temperature | Temperature Unit | Sex/Mating Type | Description | Author | Year | PubMed | DOI | Source | ||||||||||||||
1 | OB_000493 | Saccharomyces cerevisiae | BY4741 |
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decreased | -9.53% | 23.25 | 25.7 | divisions | mean | 30 | ℃ | mata | Supplemental Data Table | Steffen et al. | 2008 | 18423200 | doi:10.1016/j.cell.2008.02.037 | Lifespan Observations Database (ID: 1755) | ||||||||||||||||
2 | OB_007168 | Saccharomyces cerevisiae |
|
decreased | -25.00% | unknown | Replicative lifespan decreased by 25% in the alpha strain | Smith et al. | 2008 | 18340043 | doi:10.1101/gr.074724.107 | GenAge | |||||||||||||||||||||||
3 | OB_007169 | Saccharomyces cerevisiae |
|
decreased | -25.00% | unknown | Replicative lifespan decreased by 25% in the alpha strain | Steffen et al. | 2008 | 18423200 | doi:10.1016/j.cell.2008.02.037 | GenAge | |||||||||||||||||||||||
4 | OB_000450 | Saccharomyces cerevisiae | BY4742 |
|
decreased | -34.83% | 16 | 24.55 | divisions | mean | 30 | ℃ | matalpha | Supplemental Data Table | Steffen et al. | 2008 | 18423200 | doi:10.1016/j.cell.2008.02.037 | Lifespan Observations Database (ID: 1716) |
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:
- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
Sequences
no sequence information available
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Smith ED, Tsuchiya M, Fox LA, Dang N, Hu D, Kerr EO, Johnston ED, Tchao BN, Pak DN, Welton KL, Promislow DE, Thomas JH, Kaeberlein M, Kennedy BK:
Quantitative evidence for conserved longevity pathways between divergent eukaryotic species.
Genome Res. 2008; 18: 564-70.
PubMed (ID: 18340043), PubMed Central (ID: PMC2279244), doi:10.1101/gr.074724.107
MeSH Terms: Caenorhabditis elegans/genetics; Longevity/genetics; Saccharomyces cerevisiae/genetics - Steffen KK, MacKay VL, Kerr EO, Tsuchiya M, Hu D, Fox LA, Dang N, Johnston ED, Oakes JA, Tchao BN, Pak DN, Fields S, Kennedy BK, Kaeberlein M:
Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4.
Cell. 2008; 133: 292-302.
PubMed (ID: 18423200), PubMed Central (ID: PMC2749658), doi:10.1016/j.cell.2008.02.037
MeSH Terms: DNA-Binding Proteins/physiology; Ribosome Subunits, Large, Eukaryotic/physiology; Saccharomyces cerevisiae Proteins/physiology; Saccharomyces cerevisiae/physiology; Transcription Factors/physiology
Sources
Ageing-related Data Sources
- AgeFactDB Homology Analysis
- GenAge
- Lifespan Observations Database
Additional Data Sources
- AgeFactDB Pipeline
- GPSDB
- HomoloGene
- NCBI Taxonomy
- PubMed