Gene: MRE11 - Saccharomyces cerevisiae
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Gene Symbol | : | MRE11 | ||||||||||||||||
NCBI Gene ID | : | 855264 | ||||||||||||||||
Species | : | Saccharomyces cerevisiae | ||||||||||||||||
Gene Synonyms | : | MRE11 | Mre11p | NGS1 | RAD58 | XRS4 | YM9959.06C | YMR224C Source: GPSDB |
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Gene Homologs | : | AgaP_AGAP006797 (Anopheles gambiae) | AGOS_AFR553C (Eremothecium gossypii) | KLLA0C06930g (Kluyveromyces lactis) | MGG_09555 (Magnaporthe oryzae) | mre-11 (Caenorhabditis elegans) | MRE11 (Arabidopsis thaliana) | mre11 (Drosophila melanogaster) | MRE11 (Saccharomyces cerevisiae) | MRE11A (Bos taurus) | MRE11A (Canis lupus familiaris) | mre11a (Danio rerio) | MRE11A (Gallus gallus) | MRE11A (Homo sapiens) | MRE11A (Macaca mulatta) | Mre11a (Mus musculus) | MRE11A (Pan troglodytes) | Mre11a (Rattus norvegicus) | NCU08730 (Neurospora crassa) | Os04g0635900 (Oryza sativa) | rad32 (Schizosaccharomyces pombe) | ||||||||||||||||
Ageing Relevance Analysis | : |
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Ageing Factor Stable ID | : | AF_001225 | ||||||||||||||||
Download | : | XML |
Protein Information
no protein information available
Observations
Ageing Phenotype
Data Type 1
no ageing phenotype observation—data type 1 available
Data Type 2
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Organism | Ageing Factor | Lifespan Observation | Reference | ||||||||||||||||||||||||||||||||
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# | Observation Stable ID | Species | Strain | Gene | Compound | Other Ageing Factor | Significant Lifespan Effect | Change | Observed Lifespan | Reference Lifespan | Lifespan Unit | Measure | Temperature | Temperature Unit | Sex/Mating Type | Description | Author | Year | PubMed | DOI | Source | ||||||||||||||
1 | OB_006967 | Saccharomyces cerevisiae |
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decreased | -15.00% | unknown | Mean chronological lifespan decreased in the a strain by less than 50% but more than 15% | Laschober et al. | 2010 | 20883526 | doi:10.1111/j.1474-9726.2010.00637.x | GenAge |
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:
- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
Sequences
no sequence information available
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Laschober GT, Ruli D, Hofer E, Muck C, Carmona-Gutierrez D, Ring J, Hutter E, Ruckenstuhl C, Micutkova L, Brunauer R, Jamnig A, Trimmel D, Herndler-Brandstetter D, Brunner S, Zenzmaier C, Sampson N, Breitenbach M, Fröhlich KU, Grubeck-Loebenstein B, Berger P, Wieser M, Grillari-Voglauer R, Thallinger GG, Grillari J, Trajanoski Z, Madeo F, Lepperdinger G, Jansen-Dürr P:
Identification of evolutionarily conserved genetic regulators of cellular aging.
Aging Cell. 2010; 9: 1084-97.
PubMed (ID: 20883526), PubMed Central (ID: PMC2997327), doi:10.1111/j.1474-9726.2010.00637.x
MeSH Terms: Cell Aging/genetics; Evolution, Molecular; Gene Expression Regulation
Sources
Ageing-related Data Sources
- AgeFactDB Homology Analysis
- GenAge
Additional Data Sources
- AgeFactDB Pipeline
- GPSDB
- HomoloGene
- NCBI Taxonomy
- PubMed