Gene: NDE1 - Saccharomyces cerevisiae
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Gene Symbol |
: |
NDE1 |
NCBI Gene ID |
: |
855176 |
Species |
: |
Saccharomyces cerevisiae |
Gene Synonyms |
: |
NADH-ubiquinone reductase (H(+)-translocating) NDE1 | NDE1 | Nde1p | NDH1 | YM9375.14C | YMR145C
Source: GPSDB |
Gene Homologs |
: |
AGOS_ADR262C (Eremothecium gossypii) | KLLA0E21891g (Kluyveromyces lactis) | MGG_06276 (Magnaporthe oryzae) | NCU11397 (Neurospora crassa) | NDB2 (Arabidopsis thaliana) | NDB3 (Arabidopsis thaliana) | NDB4 (Arabidopsis thaliana) | NDE1 (Saccharomyces cerevisiae) | SPAC3A11.07 (Schizosaccharomyces pombe) |
Ageing Relevance Analysis |
: |
Observation Type |
Count |
Ageing Relevance |
Source |
Ageing Phenotype Observation—Data Type 1 |
1 |
yes (Exp. Analysis) |
GenDR |
Ageing Phenotype Observation—Data Type 2 Lifespan Effect |
|
|
|
increased |
1 |
yes (Exp. Analysis) |
Lifespan Observations Database |
Homology Analysis |
1 |
- (basis for a Comp. Analysis) |
AgeFactDB Homology Analysis |
Total |
3 |
|
|
|
Ageing Factor Stable ID |
: |
AF_001380 |
Download |
: |
XML |
Protein Information
no protein information available
Observations
Ageing Phenotype
Data Type 1
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Data Type 2
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
# |
Observation Stable ID |
Homology Group Genes |
#EGHG |
Description |
Source |
Homology Source |
1 |
OB_008660 |
|
1 |
The HomoloGene homology group 5566 contains 1 gene with experimental evidence for ageing relevance (NDE1 - Saccharomyces cerevisiae) and 8 other genes. |
AgeFactDB Homology Analysis |
HomoloGene homology group 5566 |
Sequences
no sequence information available
References
MeSH Terms:
Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms.
They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page.
MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Lin SJ, Kaeberlein M, Andalis AA, Sturtz LA, Defossez PA, Culotta VC, Fink GR, Guarente L:
Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration.
Nature. 2002; 418: 344-8.
PubMed (ID: 12124627), doi:10.1038/nature00829
MeSH Terms: Cell Aging/physiology; Cell Respiration; Energy Intake/physiology; Glucose/metabolism; Histone Deacetylases/metabolism; Saccharomyces cerevisiae/metabolism; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Trans-Activators/metabolism
- Lin SJ, Ford E, Haigis M, Liszt G, Guarente L:
Calorie restriction extends yeast life span by lowering the level of NADH.
Genes Dev. 2004; 18: 12-6.
PubMed (ID: 14724176), PubMed Central (ID: PMC314267), doi:10.1101/gad.1164804
MeSH Terms: NAD/metabolism; Saccharomyces cerevisiae/growth & development
- Li W, Sun L, Liang Q, Wang J, Mo W, Zhou B:
Yeast AMID homologue Ndi1p displays respiration-restricted apoptotic activity and is involved in chronological aging.
Mol Biol Cell. 2006; 17: 1802-11.
PubMed (ID: 16436509), PubMed Central (ID: PMC1415318), doi:10.1091/mbc.E05-04-0333
MeSH Terms: Apoptosis; Mitochondria/metabolism; NADH Dehydrogenase/metabolism; Reactive Oxygen Species/metabolism; Saccharomyces cerevisiae Proteins/metabolism; Saccharomyces cerevisiae/growth & development
Sources
Ageing-related Data Sources
Additional Data Sources