Gene: OPT2 - Saccharomyces cerevisiae
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Gene Symbol |
: |
OPT2 |
NCBI Gene ID |
: |
856324 |
Species |
: |
Saccharomyces cerevisiae |
Gene Synonyms |
: |
OPT2 | Opt2p | P9677.13 | YPR194C
Source: GPSDB |
Gene Homologs |
: |
AGOS_ACL205C (Eremothecium gossypii) | AGOS_ADL399C (Eremothecium gossypii) | NCU07894 (Neurospora crassa) | OPT2 (Saccharomyces cerevisiae) |
Ageing Relevance Analysis |
: |
Observation Type |
Count |
Ageing Relevance |
Source |
Ageing Phenotype Observation—Data Type 1 |
1 |
yes (Exp. Analysis) |
GenAge |
Homology Analysis |
1 |
- (basis for a Comp. Analysis) |
AgeFactDB Homology Analysis |
Total |
2 |
|
|
|
Ageing Factor Stable ID |
: |
AF_001514 |
Download |
: |
XML |
Protein Information
no protein information available
Observations
Ageing Phenotype
Data Type 1
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Data Type 2
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
|
Organism |
Ageing Factor |
Lifespan Observation |
|
Reference |
# |
Observation Stable ID |
Species |
Strain |
Gene |
Compound |
Other Ageing Factor |
Significant Lifespan Effect |
Change |
Observed Lifespan |
Reference Lifespan |
Lifespan Unit |
Measure |
Temperature |
Temperature Unit |
Sex/Mating Type |
Description |
Author |
Year |
PubMed |
DOI |
Source |
1 |
OB_007563 |
Saccharomyces cerevisiae |
|
Gene Symbol |
Species |
NCBI Gene ID |
Allele Type |
Allele Name |
Reference Allele Type |
Allele Change |
OPT2 |
Saccharomyces cerevisiae |
856324 |
Deletion |
- |
wildtype |
yes |
|
|
|
increased |
9.00% |
|
|
|
maximum |
|
|
|
OPT2 deletion increases mean and maximum replicative lifespan under ad libitum. This is not further extended by dietary restriction. |
Wuttke et al. |
2012 |
22912585 |
doi:10.1371/journal.pgen.1002834 |
GenAge |
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
# |
Observation Stable ID |
Homology Group Genes |
#EGHG |
Description |
Source |
Homology Source |
1 |
OB_008217 |
|
1 |
The HomoloGene homology group 68989 contains 1 gene with experimental evidence for ageing relevance (OPT2 - Saccharomyces cerevisiae) and 3 other genes. |
AgeFactDB Homology Analysis |
HomoloGene homology group 68989 |
Sequences
no sequence information available
References
MeSH Terms:
Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms.
They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page.
MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Wuttke D, Connor R, Vora C, Craig T, Li Y, Wood S, Vasieva O, Shmookler Reis R, Tang F, de Magalhães JP:
Dissecting the gene network of dietary restriction to identify evolutionarily conserved pathways and new functional genes.
PLoS Genet. 2012; 8: e1002834.
PubMed (ID: 22912585), PubMed Central (ID: PMC3415404), doi:10.1371/journal.pgen.1002834
MeSH Terms: Aging/genetics; Caloric Restriction; Gametogenesis/genetics; Gene Regulatory Networks; Longevity/genetics
Sources
Ageing-related Data Sources
Additional Data Sources