Gene: UGA3 - Saccharomyces cerevisiae
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Gene Symbol | : | UGA3 | ||||||||||||||||||||||||
NCBI Gene ID | : | 851384 | ||||||||||||||||||||||||
Species | : | Saccharomyces cerevisiae | ||||||||||||||||||||||||
Gene Synonyms | : | UGA3 | Uga3p | YDL170W Source: GPSDB |
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Gene Homologs | : | KLLA0E19603g (Kluyveromyces lactis) | SPCC965.10 (Schizosaccharomyces pombe) | UGA3 (Saccharomyces cerevisiae) | ||||||||||||||||||||||||
Ageing Relevance Analysis | : |
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Ageing Factor Stable ID | : | AF_002465 | ||||||||||||||||||||||||
Download | : | XML |
Protein Information
no protein information available
Observations
Ageing Phenotype
Data Type 1
no ageing phenotype observation—data type 1 available
Data Type 2
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Organism | Ageing Factor | Lifespan Observation | Reference | ||||||||||||||||||||||||||||||||
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# | Observation Stable ID | Species | Strain | Gene | Compound | Other Ageing Factor | Significant Lifespan Effect | Change | Observed Lifespan | Reference Lifespan | Lifespan Unit | Measure | Temperature | Temperature Unit | Sex/Mating Type | Description | Author | Year | PubMed | DOI | Source | ||||||||||||||
1 | OB_007546 | Saccharomyces cerevisiae |
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increased | 75.00% | unknown | Mean replicative lifespan increased by 75% in the alpha strain | Yoshida et al. | 2010 | 20550517 | doi:10.1111/j.1474-9726.2010.00590.x | GenAge | |||||||||||||||||||||||
2 | OB_002667 | Saccharomyces cerevisiae | BY4742 |
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increased | 74.61% | 33.7 | 19.3 | divisions | mean | 30 | ℃ | matalpha | Deletion of URH1, UGA3, or FZF1 was found to increase life span. These genes and four others that did not increase life span were predicted to increase life span based on their metabolimic profile. | Yoshida et al. | 2010 | 20550517 | doi:10.1111/j.1474-9726.2010.00590.x | Lifespan Observations Database (ID: 3959) |
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:
- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
# | Observation Stable ID | Homology Group Genes | #EGHG | Description | Source | Homology Source | ||||||||||||
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1 | OB_008218 |
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1 | The HomoloGene homology group 48590 contains 1 gene with experimental evidence for ageing relevance (UGA3 - Saccharomyces cerevisiae) and 2 other genes. | AgeFactDB Homology Analysis | HomoloGene homology group 48590 |
Sequences
no sequence information available
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Yoshida R, Tamura T, Takaoka C, Harada K, Kobayashi A, Mukai Y, Fukusaki E:
Metabolomics-based systematic prediction of yeast lifespan and its application for semi-rational screening of ageing-related mutants.
Aging Cell. 2010; 9: 616-25.
PubMed (ID: 20550517), doi:10.1111/j.1474-9726.2010.00590.x
MeSH Terms: Genetic Testing/methods; Metabolomics/methods; Mutation/genetics; Saccharomyces cerevisiae/genetics; Saccharomyces cerevisiae/metabolism
Sources
Ageing-related Data Sources
- AgeFactDB Homology Analysis
- GenAge
- Lifespan Observations Database
Additional Data Sources
- AgeFactDB Pipeline
- GPSDB
- HomoloGene
- NCBI Taxonomy
- PubMed