Gene: MED37A - Arabidopsis thaliana
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Gene Symbol | : | MED37A | ||||||||||||
NCBI Gene ID | : | 832950 | ||||||||||||
Species | : | Arabidopsis thaliana | ||||||||||||
Gene Synonyms | : | AT5G28540 | At5g28540 | AT5G28540.1 | BIP1 | HSP70-11 | Luminal-binding protein 1 | MED37_5 | MED37A | T26D3.10 | T26D3_10 | T26D3_50 Source: GPSDB |
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Gene Homologs | : | AgaP_AGAP004192 (Anopheles gambiae) | AGOS_ACR038W (Eremothecium gossypii) | bip1 (Schizosaccharomyces pombe) | Hsc70-3 (Drosophila melanogaster) | hsp-3 (Caenorhabditis elegans) | hsp-4 (Caenorhabditis elegans) | HSPA5 (Bos taurus) | HSPA5 (Canis lupus familiaris) | hspa5 (Danio rerio) | HSPA5 (Gallus gallus) | HSPA5 (Homo sapiens) | HSPA5 (Macaca mulatta) | Hspa5 (Mus musculus) | HSPA5 (Pan troglodytes) | Hspa5 (Rattus norvegicus) | KAR2 (Saccharomyces cerevisiae) | KLLA0D09559g (Kluyveromyces lactis) | MED37A (Arabidopsis thaliana) | MED37F (Arabidopsis thaliana) | MGG_02503 (Magnaporthe oryzae) | NCU03982 (Neurospora crassa) | Os02g0115900 (Oryza sativa) | ||||||||||||
Ageing Relevance Analysis | : |
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Ageing Factor Stable ID | : | AF_003561 | ||||||||||||
Download | : | XML |
Protein Information
Protein Name | Species | UniProt Accession Number | UniProt Entry Name | Protein Function | Sequence |
---|---|---|---|---|---|
Mediator of RNA polymerase II transcription subunit 37a | Arabidopsis thaliana | Q9LKR3 (UniProtKB/Swiss-Prot) | MD37A_ARATH (UniProtKB/Swiss-Prot) | In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. | View |
Observations
Ageing Phenotype
Data Type 1
no ageing phenotype observation—data type 1 available
Data Type 2
no ageing phenotype observation—data type 2 available
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:
- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
Sequences
MD37A_ARATH | Q9LKR3 | Mediator of RNA polymerase II transcription subunit 37a (Arabidopsis thaliana) from UniProtKB/Swiss-Prot Length: 669 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 MD37A_ARATH 1 MARSFGANSTVVLAIIFFGCLFALSSAIEEATKLGSVIGIDLGTTYSCVGVYKNGHVEIIANDQGNRITPSWVGFTDSERLIGEAAKNQAAVNPERTVFDVKRLIGRKFEDKEVQKDRKLVPYQIVNKDGKPYIQVKIKDGETKVFSPEEISAMILTKMKETAEAYLGKKIKDAVVTVPAYFNDAQRQATKDAGVIAGLNVARIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSVLTIDNGVFEVLSTNGDTHLGGEDFDHRVMEYFIKLIKKKHQKDISKDNKALGKLRRECERAKRALSSQHQVRVEIESLFDGVDFSEPLTRARFEELNNDLFRKTMGPVKKAMDDAGLQKSQIDEIVLVGGSTRIPKVQQLLKDFFEGKEPNKGVNPDEAVAYGAAVQGGILSGEGGDETKDILLLDVAPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFTTYQDQQTTVSIQVFEGERSLTKDCRLLGKFDLNGIPPAPRGTPQIEVTFEVDANGILNVKAEDKASGKSEKITITNEKGRLSQEEIDRMVKEAEEFAEEDKKVKEKIDARNALETYVYNMKNQVNDKDKLADKLEGDEKEKIEAATKEALEWLDENQNSEKEEYDEKLKEVEAVCNPIITAVYQRSGGAPGGAGGESSTEEEDESHDEL 669
References
no reference information available
Sources
Ageing-related Data Sources
- AgeFactDB Homology Analysis
Additional Data Sources
- AgeFactDB Pipeline
- GPSDB
- HomoloGene
- UniProtKB/Swiss-Prot