Gene: BRE5 - Saccharomyces cerevisiae
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Gene Symbol | : | BRE5 | ||||||||||||||||||||||||
NCBI Gene ID | : | 855787 | ||||||||||||||||||||||||
Species | : | Saccharomyces cerevisiae | ||||||||||||||||||||||||
Gene Synonyms | : | BRE5 | Bre5p | N3465 | YNR051C Source: GPSDB |
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Gene Homologs | : | AGOS_ABR118C (Eremothecium gossypii) | BRE5 (Saccharomyces cerevisiae) | KLLA0C18799g (Kluyveromyces lactis) | ||||||||||||||||||||||||
Ageing Relevance Analysis | : |
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Ageing Factor Stable ID | : | AF_004078 | ||||||||||||||||||||||||
Download | : | XML |
Protein Information
no protein information available
Observations
Ageing Phenotype
Data Type 1
no ageing phenotype observation—data type 1 available
Data Type 2
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Organism | Ageing Factor | Lifespan Observation | Reference | ||||||||||||||||||||||||||||||||
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# | Observation Stable ID | Species | Strain | Gene | Compound | Other Ageing Factor | Significant Lifespan Effect | Change | Observed Lifespan | Reference Lifespan | Lifespan Unit | Measure | Temperature | Temperature Unit | Sex/Mating Type | Description | Author | Year | PubMed | DOI | Source | ||||||||||||||
1 | OB_000047 | Saccharomyces cerevisiae | BY4741 |
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increased | 30.00% | divisions | mean | 30 | ℃ | mata | 13 genes were identified as long-lived in both haploid mating types from a screen of 564 single-gene deletion strains from the yeast ORF deletion collection. | Kaeberlein et al. | 2005 | 16293764 | doi:10.1126/science.1115535 | Lifespan Observations Database (ID: 1049) | ||||||||||||||||||
2 | OB_005681 | Saccharomyces cerevisiae |
|
increased | 30.00% | unknown | Deletion increased mean replicative lifespan by 30%. | Kaeberlein et al. | 2005 | 16293764 | doi:10.1126/science.1115535 | GenAge | |||||||||||||||||||||||
3 | OB_000046 | Saccharomyces cerevisiae | BY4742 |
|
increased | 29.00% | divisions | mean | 30 | ℃ | matalpha | 13 genes were identified as long-lived in both haploid mating types from a screen of 564 single-gene deletion strains from the yeast ORF deletion collection. | Kaeberlein et al. | 2005 | 16293764 | doi:10.1126/science.1115535 | Lifespan Observations Database (ID: 1048) | ||||||||||||||||||
4 | OB_005682 | Saccharomyces cerevisiae |
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decreased | unknown | Mean replicative lifespan decreased in the alpha and a strain | Fabrizio et al. | 2010 | 20657825 | doi:10.1371/journal.pgen.1001024 | GenAge |
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:
- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
# | Observation Stable ID | Homology Group Genes | #EGHG | Description | Source | Homology Source | ||||||||||||
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1 | OB_008869 |
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1 | The HomoloGene homology group 40169 contains 1 gene with experimental evidence for ageing relevance (BRE5 - Saccharomyces cerevisiae) and 2 other genes. | AgeFactDB Homology Analysis | HomoloGene homology group 40169 |
Sequences
no sequence information available
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Kaeberlein M, Powers RW, Steffen KK, Westman EA, Hu D, Dang N, Kerr EO, Kirkland KT, Fields S, Kennedy BK:
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients.
Science. 2005; 310: 1193-6.
PubMed (ID: 16293764), doi:10.1126/science.1115535
MeSH Terms: Protein Kinases/metabolism; Saccharomyces cerevisiae Proteins/physiology; Saccharomyces cerevisiae/physiology - Fabrizio P, Hoon S, Shamalnasab M, Galbani A, Wei M, Giaever G, Nislow C, Longo VD:
Genome-wide screen in Saccharomyces cerevisiae identifies vacuolar protein sorting, autophagy, biosynthetic, and tRNA methylation genes involved in life span regulation.
PLoS Genet. 2010; 6: e1001024.
PubMed (ID: 20657825), PubMed Central (ID: PMC2904796), doi:10.1371/journal.pgen.1001024
MeSH Terms: Genome, Fungal; Longevity/genetics; Saccharomyces cerevisiae/genetics
Sources
Ageing-related Data Sources
- AgeFactDB Homology Analysis
- GenAge
- Lifespan Observations Database
Additional Data Sources
- AgeFactDB Pipeline
- GPSDB
- HomoloGene
- NCBI Taxonomy
- PubMed