Gene: PDPK1 - Arabidopsis thaliana
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Gene Symbol | : | PDPK1 | ||||||||||||
NCBI Gene ID | : | 830330 | ||||||||||||
Species | : | Arabidopsis thaliana | ||||||||||||
Gene Synonyms | : | 3'-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1 | 3'-phosphoinositide-dependent protein kinase 1 | 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1 | AT5G04510 | At5g04510 | AT5G04510.1 | AT5G04510.2 | ATPDK1 | PDK1 | PDPK1 | T32M21.110 | T32M21_110 Source: GPSDB |
||||||||||||
Gene Homologs | : | AgaP_AGAP001471 (Anopheles gambiae) | Os01g0872800 (Oryza sativa) | pdk-1 (Caenorhabditis elegans) | Pdk1 (Drosophila melanogaster) | PDPK1 (Arabidopsis thaliana) | PDPK1 (Bos taurus) | PDPK1 (Canis lupus familiaris) | PDPK1 (Gallus gallus) | PDPK1 (Homo sapiens) | Pdpk1 (Mus musculus) | Pdpk1 (Rattus norvegicus) | pdpk1b (Danio rerio) | PDPK2 (Arabidopsis thaliana) | ||||||||||||
Ageing Relevance Analysis | : |
|
||||||||||||
Ageing Factor Stable ID | : | AF_004772 | ||||||||||||
Download | : | XML |
Protein Information
Protein Name | Species | UniProt Accession Number | UniProt Entry Name | Protein Function | Sequence |
---|---|---|---|---|---|
3'-phosphoinositide-dependent protein kinase 1 | Arabidopsis thaliana | F4JWB0 (UniProtKB/TrEMBL) | F4JWB0_ARATH (UniProtKB/TrEMBL) | View | |
3-phosphoinositide-dependent protein kinase 1 | Arabidopsis thaliana | Q9XF67 (UniProtKB/Swiss-Prot) | PDPK1_ARATH (UniProtKB/Swiss-Prot) | May couple lipid signals to the activation-loop phosphorylation of several protein kinases of the so-called AGC kinase family. Interacts via its pleckstrin homology domain with phosphatidic acid, PtdIns3P and PtdIns(3,4)P2 and to a lesser extent with PtdIns(4,5)P2 and PtdIns4P. May play a general role in signaling processes controlling the pathogen/stress response, polar auxin transport and development. Transphosphorylates the AGC protein kinases OXI1/AGC2-1, PK1/S6K1, PK19/S6K2 and PID resulting in their activation. | View |
Observations
Ageing Phenotype
Data Type 1
no ageing phenotype observation—data type 1 available
Data Type 2
no ageing phenotype observation—data type 2 available
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:
- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
# | Observation Stable ID | Homology Group Genes | #EGHG | Description | Source | Homology Source |
---|---|---|---|---|---|---|
1 | OB_008186 | 2 | The HomoloGene homology group 37643 contains 2 genes with experimental evidence for ageing relevance (PDPK1 - Homo sapiens | pdk-1 - Caenorhabditis elegans) and 11 other genes. | AgeFactDB Homology Analysis | HomoloGene homology group 37643 |
Sequences
F4JWB0_ARATH | F4JWB0 | 3'-phosphoinositide-dependent protein kinase 1 (Arabidopsis thaliana) from UniProtKB/TrEMBL Length: 408 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 F4JWB0_ARATH 1 MLAMEKEFDSKLVLQGNSSNGANVSRSKSFSFKAPQENFTSHDFEFGKIYGVGSYSKVVRAKKKETGTVYALKIMDKKFITKENKTAYVKLERIVLDQLEHPGIIKLYFTFQDTSSLYMALESCEGGELFDQITRKGRLSEDEARFYTAEVVDALEYIHSMGLIHRDIKPENLLLTSDGHIKIADFGSVKPMQDSQITVLPNAASDDKACTFVGTAAYVPPEVLNSSPATFGNDLWALGCTLYQMLSGTSPFKDASEWLIFQRIIARDIKFPNHFSEAARDLIDRLLDTEPSRRPGAGSEGYVALKRHPFFNGVDWKNLRSQTPPKLAPDPASQTASPERDDTHGSPWNLTHIGDSLATQNEGHSAPPTSSESSGSITRLASIDSFDSRWWGHLSFICFLGSNLVQSS 408
PDPK1_ARATH | Q9XF67 | 3-phosphoinositide-dependent protein kinase 1 (Arabidopsis thaliana) from UniProtKB/Swiss-Prot Length: 491 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 PDPK1_ARATH 1 MLAMEKEFDSKLVLQGNSSNGANVSRSKSFSFKAPQENFTSHDFEFGKIYGVGSYSKVVRAKKKETGTVYALKIMDKKFITKENKTAYVKLERIVLDQLEHPGIIKLYFTFQDTSSLYMALESCEGGELFDQITRKGRLSEDEARFYTAEVVDALEYIHSMGLIHRDIKPENLLLTSDGHIKIADFGSVKPMQDSQITVLPNAASDDKACTFVGTAAYVPPEVLNSSPATFGNDLWALGCTLYQMLSGTSPFKDASEWLIFQRIIARDIKFPNHFSEAARDLIDRLLDTEPSRRPGAGSEGYVALKRHPFFNGVDWKNLRSQTPPKLAPDPASQTASPERDDTHGSPWNLTHIGDSLATQNEGHSAPPTSSESSGSITRLASIDSFDSRWQQFLEPGESVLMISAVKKLQKITSKKVQLILTNKPKLIYVDPSKLVVKGNIIWSDNSNDLNVVVTSPSHFKICTPKKVLSFEDAKQRASVWKKAIETLQNR 491
References
no reference information available
Sources
Ageing-related Data Sources
- AgeFactDB Homology Analysis
Additional Data Sources
- AgeFactDB Pipeline
- GPSDB
- HomoloGene
- UniProtKB/Swiss-Prot
- UniProtKB/TrEMBL