Gene: rpl-6 - Caenorhabditis elegans
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Gene Symbol | : | rpl-6 | ||||||||||||||||||||
NCBI Gene ID | : | 176015 | ||||||||||||||||||||
Species | : | Caenorhabditis elegans | ||||||||||||||||||||
Gene Synonyms | : | CE00744 | CELE_R151.3 | Protein RPL-6 | R151.3 | R151.3.1 | R151.3.2 | rpl-6 | WP:CE00744 Source: GPSDB |
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Gene Homologs | : | AgaP_AGAP001911 (Anopheles gambiae) | AGOS_AER149W (Eremothecium gossypii) | Gm5428 (Mus musculus) | KLLA0B04686g (Kluyveromyces lactis) | LOC712820 (Macaca mulatta) | LOC737972 (Pan troglodytes) | MGG_04444 (Magnaporthe oryzae) | NCU02707 (Neurospora crassa) | Os02g0591700 (Oryza sativa) | Os04g0473400 (Oryza sativa) | rpl-6 (Caenorhabditis elegans) | RPL6 (Bos taurus) | RPL6 (Canis lupus familiaris) | rpl6 (Danio rerio) | RpL6 (Drosophila melanogaster) | RPL6 (Gallus gallus) | RPL6 (Homo sapiens) | RPL6 (Macaca mulatta) | Rpl6 (Mus musculus) | Rpl6 (Rattus norvegicus) | rpl6 (Schizosaccharomyces pombe) | RPL6A (Arabidopsis thaliana) | RPL6A (Saccharomyces cerevisiae) | RPL6B (Arabidopsis thaliana) | RPL6B (Saccharomyces cerevisiae) | RPL6C (Arabidopsis thaliana) | ||||||||||||||||||||
Ageing Relevance Analysis | : |
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Ageing Factor Stable ID | : | AF_004829 | ||||||||||||||||||||
Download | : | XML |
Protein Information
Protein Name | Species | UniProt Accession Number | UniProt Entry Name | Protein Function | Sequence |
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60S ribosomal protein L6 | Caenorhabditis elegans | P47991 (UniProtKB/Swiss-Prot) | RL6_CAEEL (UniProtKB/Swiss-Prot) | View |
Observations
Ageing Phenotype
Data Type 1
no ageing phenotype observation—data type 1 available
Data Type 2
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Organism | Ageing Factor | Lifespan Observation | Reference | ||||||||||||||||||||||||||||||||
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# | Observation Stable ID | Species | Strain | Gene | Compound | Other Ageing Factor | Significant Lifespan Effect | Change | Observed Lifespan | Reference Lifespan | Lifespan Unit | Measure | Temperature | Temperature Unit | Sex/Mating Type | Description | Author | Year | PubMed | DOI | Source | ||||||||||||||
1 | OB_001528 | Caenorhabditis elegans | N2 |
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increased | 20.10% | 24.5 | 20.4 | days | mean | 20 | ℃ | hermaphrodite | RNA knockdown increased lifespan 20%. | Hansen et al. | 2007 | 17266679 | doi:10.1111/j.1474-9726.2006.00267.x | Lifespan Observations Database (ID: 2871) | ||||||||||||||||
2 | OB_001529 | Caenorhabditis elegans | N2 |
|
increased | 17.99% | 22.3 | 18.9 | days | mean | hermaphrodite | RNA knockdown increased lifespan 18%. | Hansen et al. | 2007 | 17266679 | doi:10.1111/j.1474-9726.2006.00267.x | Lifespan Observations Database (ID: 2872) |
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:
- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
Sequences
RL6_CAEEL | P47991 | 60S ribosomal protein L6 (Caenorhabditis elegans) from UniProtKB/Swiss-Prot Length: 217 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 RL6_CAEEL 1 MVGKRNLPVISRNFDLSPGVLRFSASRLRLKKGEKKPKFTKDTSAKLPKLQRNGTKFALGHSKTVTLRKTLTPGTVLIVLAGRHKGKRVVFLKQLPQSGLLLVTGPHKINGFPLRRIGQAFVIATSLKVNVSGVKIPEHINDEYFKRKSTAQKTGKNIFASGKTEYTVSEQRKKDIKTVDAPILAAIKKHPEHKFLFGYLGTRFSLGKNQYPHKMQF 217
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Hansen M, Taubert S, Crawford D, Libina N, Lee SJ, Kenyon C:
Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans.
Aging Cell. 2007; 6: 95-110.
PubMed (ID: 17266679), doi:10.1111/j.1474-9726.2006.00267.x
MeSH Terms: Caenorhabditis elegans/genetics; Caenorhabditis elegans/metabolism; Gene Expression Regulation/genetics; Longevity/genetics; Protein Biosynthesis/genetics; Saccharomyces cerevisiae Proteins/metabolism
Sources
Ageing-related Data Sources
- AgeFactDB Homology Analysis
- Lifespan Observations Database
Additional Data Sources
- AgeFactDB Pipeline
- GPSDB
- HomoloGene
- NCBI Taxonomy
- PubMed
- UniProtKB/Swiss-Prot