Gene: lbp-9 - Caenorhabditis elegans
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Gene Symbol | : | lbp-9 | ||||||||||||||||||||||||
NCBI Gene ID | : | 178686 | ||||||||||||||||||||||||
Species | : | Caenorhabditis elegans | ||||||||||||||||||||||||
Gene Synonyms | : | CE26077 | CE39188 | CELE_Y40B10A.1 | lbp-9 | Protein LBP-9 | WP:CE26077 | WP:CE39188 | Y40B10A.1 | Y40B10A.1a | Y40B10A.1b | Y40B10A.1b.1 | Y40B10A.1b.2 Source: GPSDB |
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Gene Homologs | : | fabp11a (Danio rerio) | fabp11b (Danio rerio) | lbp-9 (Caenorhabditis elegans) | LOC100334189 (Danio rerio) | LOC100536788 (Danio rerio) | PMP2 (Bos taurus) | PMP2 (Canis lupus familiaris) | PMP2 (Gallus gallus) | PMP2 (Homo sapiens) | PMP2 (Macaca mulatta) | Pmp2 (Mus musculus) | PMP2 (Pan troglodytes) | Pmp2 (Rattus norvegicus) | ||||||||||||||||||||||||
Ageing Relevance Analysis | : |
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Ageing Factor Stable ID | : | AF_005723 | ||||||||||||||||||||||||
Download | : | XML |
Protein Information
Protein Name | Species | UniProt Accession Number | UniProt Entry Name | Protein Function | Sequence |
---|---|---|---|---|---|
Fatty acid-binding protein homolog 9 | Caenorhabditis elegans | Q965W1 (UniProtKB/Swiss-Prot) | FABP9_CAEEL (UniProtKB/Swiss-Prot) | View | |
Protein LBP-9, isoform b | Caenorhabditis elegans | Q3LFN1 (UniProtKB/TrEMBL) | Q3LFN1_CAEEL (UniProtKB/TrEMBL) | View |
Observations
Ageing Phenotype
Data Type 1
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
# | Observation Stable ID | Species | Gene | Other Ageing Factor | Description | PubMed | Source | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
1 | OB_005496 | Caenorhabditis elegans |
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RNA interference resulted in decreased lifespan and earlier accumulation of lipofuscin. | 16673436 | GenAge |
Data Type 2
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Organism | Ageing Factor | Lifespan Observation | Reference | ||||||||||||||||||||||||||||||||
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# | Observation Stable ID | Species | Strain | Gene | Compound | Other Ageing Factor | Significant Lifespan Effect | Change | Observed Lifespan | Reference Lifespan | Lifespan Unit | Measure | Temperature | Temperature Unit | Sex/Mating Type | Description | Author | Year | PubMed | DOI | Source | ||||||||||||||
1 | OB_003852 | Caenorhabditis elegans |
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increased | 13.00% | RNA interference resulted in 13% decreased lifespan and earlier accumulation of lipofuscin. | Ha et al. | 2006 | 16673436 | doi:10.1002/pmic.200500395 | Lifespan Observations Database (ID: 573) | ||||||||||||||||||||||||
2 | OB_005497 | Caenorhabditis elegans |
|
decreased | unknown | RNA interference resulted in decreased lifespan and earlier accumulation of lipofuscin. | Ha et al. | 2006 | 16673436 | doi:10.1002/pmic.200500395 | GenAge |
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:
- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
# | Observation Stable ID | Homology Group Genes | #EGHG | Description | Source | Homology Source |
---|---|---|---|---|---|---|
1 | OB_009274 | 1 | The HomoloGene homology group 20589 contains 1 gene with experimental evidence for ageing relevance (lbp-9 - Caenorhabditis elegans) and 12 other genes. | AgeFactDB Homology Analysis | HomoloGene homology group 20589 |
Sequences
FABP9_CAEEL | Q965W1 | Fatty acid-binding protein homolog 9 (Caenorhabditis elegans) from UniProtKB/Swiss-Prot Length: 152 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 FABP9_CAEEL 1 MLSAFFKTAHCALRNMPIQTDLVGKWNFVSSENFDEYLKEVGVGWAIRTIATKTKPALEFAVNGDEWTMNSNSTFKNYTLKWKLGTASDEKTADGRDVSSVFSIENDHLVQIETGKGGGKDSRIERYIENGKLVIVCTCNGVKCTRVYEKAA 152
Q3LFN1_CAEEL | Q3LFN1 | Protein LBP-9, isoform b (Caenorhabditis elegans) from UniProtKB/TrEMBL Length: 137 10 20 30 40 50 60 70 80 90 100 110 120 130 Q3LFN1_CAEEL 1 MPIQTDLVGKWNFVSSENFDEYLKEVGVGWAIRTIATKTKPALEFAVNGDEWTMNSNSTFKNYTLKWKLGTASDEKTADGRDVSSVFSIENDHLVQIETGKGGGKDSRIERYIENGKLVIVCTCNGVKCTRVYEKAA 137
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Ha MK, Soo Cho J, Baik OR, Lee KH, Koo HS, Chung KY:
Caenorhabditis elegans as a screening tool for the endothelial cell-derived putative aging-related proteins detected by proteomic analysis.
Proteomics. 2006; 6: 3339-51.
PubMed (ID: 16673436), doi:10.1002/pmic.200500395
MeSH Terms: Caenorhabditis elegans Proteins/physiology; Caenorhabditis elegans/physiology; Cell Aging/physiology; Endothelial Cells/physiology
Sources
Ageing-related Data Sources
- AgeFactDB Curator
- AgeFactDB Homology Analysis
- GenAge
- Lifespan Observations Database
Additional Data Sources
- UniProtKB/Swiss-Prot
- UniProtKB/TrEMBL
- AgeFactDB Pipeline
- GPSDB
- HomoloGene
- NCBI Taxonomy
- PubMed