Gene: YOR135W - Saccharomyces cerevisiae
Summary
Gene Symbol | : | YOR135W | ||||||||||||||||
NCBI Gene ID | : | |||||||||||||||||
Species | : | Saccharomyces cerevisiae | ||||||||||||||||
Gene Synonyms | : | |||||||||||||||||
Gene Homologs | : | |||||||||||||||||
Ageing Relevance Analysis | : |
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Ageing Factor Stable ID | : | AF_008659 | ||||||||||||||||
Download | : | XML |
* Ageing factors from different sources are merged, if possible. Genes are merged by their NCBI Gene ID, if assigned and otherwise by the combination of the gene symbol and species name. The latter approach is less reliable than using the NCBI Gene ID. This gene has no NCBI gene ID assigned. Therefore it is possible that it is already included in AgeFactDB under a different gene symbol or NCBI Gene ID. The missing NCBI Gene ID is also the reason for fact that one or more possible synonym groups are found.
Protein Information
Observations
Ageing Phenotype
Data Type 1
Data Type 2
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Organism | Ageing Factor | Lifespan Observation | Reference | ||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
# | Observation Stable ID | Species | Strain | Gene | Compound | Other Ageing Factor | Significant Lifespan Effect | Change | Observed Lifespan | Reference Lifespan | Lifespan Unit | Measure | Temperature | Temperature Unit | Sex/Mating Type | Description | Author | Year | PubMed | DOI | Source | ||||||||||||||
1 | OB_000079 | Saccharomyces cerevisiae | BY4742 |
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increased | 22.00% | divisions | mean | 30 | ℃ | matalpha | 13 genes were identified as long-lived in both haploid mating types from a screen of 564 single-gene deletion strains from the yeast ORF deletion collection. YOR135W encodes a dubious ORF that overlaps IDH2 and likely extends replicative life span due to loss of function of IDH2. | Kaeberlein et al. | 2005 | 16293764 | doi:10.1126/science.1115535 | Lifespan Observations Database (ID: 1078) | ||||||||||||||||||
2 | OB_000078 | Saccharomyces cerevisiae | BY4741 |
|
increased | 18.00% | divisions | mean | 30 | ℃ | mata | 13 genes were identified as long-lived in both haploid mating types from a screen of 564 single-gene deletion strains from the yeast ORF deletion collection. YOR135W encodes a dubious ORF that overlaps IDH2 and likely extends replicative life span due to loss of function of IDH2. | Kaeberlein et al. | 2005 | 16293764 | doi:10.1126/science.1115535 | Lifespan Observations Database (ID: 1077) |
Homology Analysis
Sequences
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Kaeberlein M, Powers RW, Steffen KK, Westman EA, Hu D, Dang N, Kerr EO, Kirkland KT, Fields S, Kennedy BK:
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients.
Science. 2005; 310: 1193-6.
PubMed (ID: 16293764), doi:10.1126/science.1115535
MeSH Terms: Protein Kinases/metabolism; Saccharomyces cerevisiae Proteins/physiology; Saccharomyces cerevisiae/physiology