Gene: SPT4 - Saccharomyces cerevisiae
Last modified: Dec 09, 2014. Release 1 • Page created: Jun 02, 2024
Summary
Gene Symbol | : | SPT4 | ||||||||||||||||||||||||
NCBI Gene ID | : | 852955 | ||||||||||||||||||||||||
Species | : | Saccharomyces cerevisiae | ||||||||||||||||||||||||
Gene Synonyms | : | |||||||||||||||||||||||||
Gene Homologs | : | AGOS_AFR576C (Eremothecium gossypii) | KLLA0B07997g (Kluyveromyces lactis) | SPT4 (Saccharomyces cerevisiae) | ||||||||||||||||||||||||
Ageing Relevance Analysis | : |
|
||||||||||||||||||||||||
Ageing Factor Stable ID | : | AF_008667 | ||||||||||||||||||||||||
Download | : | XML |
Protein Information
no protein information available
Observations
Ageing Phenotype
Data Type 1
no ageing phenotype observation—data type 1 available
Data Type 2
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Organism | Ageing Factor | Lifespan Observation | Reference | ||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
# | Observation Stable ID | Species | Strain | Gene | Compound | Other Ageing Factor | Significant Lifespan Effect | Change | Observed Lifespan | Reference Lifespan | Lifespan Unit | Measure | Temperature | Temperature Unit | Sex/Mating Type | Description | Author | Year | PubMed | DOI | Source | ||||||||||||||
1 | OB_000175 | Saccharomyces cerevisiae | BY4742 |
|
increased | 40.90% | divisions | mean | 30 | ℃ | matalpha | From Table 2. Conserved longevity genes. 25 replicative life span extending single-gene deletions in the BY4742 strain background were identified that correspond to known aging-related genes in Caenorhabditis elegans. | Smith et al. | 2008 | 18340043 | doi:10.1101/gr.074724.107 | Lifespan Observations Database (ID: 1185) | ||||||||||||||||||
2 | OB_007518 | Saccharomyces cerevisiae |
|
increased | 40.00% | unknown | Replicative lifespan increased by 40% in alpha and a strains | Smith et al. | 2008 | 18340043 | doi:10.1101/gr.074724.107 | GenAge | |||||||||||||||||||||||
3 | OB_000216 | Saccharomyces cerevisiae | BY4741 |
|
increased | 38.70% | divisions | mean | 30 | ℃ | mata | From Table 2. Conserved longevity genes. 25 replicative life span extending single-gene deletions in the BY4742 strain background were identified that correspond to known aging-related genes in Caenorhabditis elegans. | Smith et al. | 2008 | 18340043 | doi:10.1101/gr.074724.107 | Lifespan Observations Database (ID: 1221) |
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:
- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
# | Observation Stable ID | Homology Group Genes | #EGHG | Description | Source | Homology Source | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | OB_009229 |
|
1 | The HomoloGene homology group 39095 contains 1 gene with experimental evidence for ageing relevance (SPT4 - Saccharomyces cerevisiae) and 2 other genes. | AgeFactDB Homology Analysis | HomoloGene homology group 39095 |
Sequences
no sequence information available
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Smith ED, Tsuchiya M, Fox LA, Dang N, Hu D, Kerr EO, Johnston ED, Tchao BN, Pak DN, Welton KL, Promislow DE, Thomas JH, Kaeberlein M, Kennedy BK:
Quantitative evidence for conserved longevity pathways between divergent eukaryotic species.
Genome Res. 2008; 18: 564-70.
PubMed (ID: 18340043), PubMed Central (ID: PMC2279244), doi:10.1101/gr.074724.107
MeSH Terms: Caenorhabditis elegans/genetics; Longevity/genetics; Saccharomyces cerevisiae/genetics
Sources
Ageing-related Data Sources
- AgeFactDB Homology Analysis
- GenAge
- Lifespan Observations Database
Additional Data Sources
- AgeFactDB Pipeline
- HomoloGene
- NCBI Taxonomy
- PubMed