Gene: TIF1 - Saccharomyces cerevisiae
Last modified: Dec 09, 2014. Release 1 • Page created: Jun 02, 2024
Summary
Gene Symbol |
: |
TIF1 |
NCBI Gene ID |
: |
853933 |
Species |
: |
Saccharomyces cerevisiae |
Gene Synonyms |
: |
|
Gene Homologs |
: |
AGOS_ACR253C (Eremothecium gossypii) | EIF4A1 (Bos taurus) | EIF4A1 (Canis lupus familiaris) | EIF4A1 (Homo sapiens) | EIF4A1 (Macaca mulatta) | Eif4a1 (Mus musculus) | EIF4A1 (Pan troglodytes) | Eif4a1 (Rattus norvegicus) | eif4a1a (Danio rerio) | eif4a1b (Danio rerio) | KLLA0A05731g (Kluyveromyces lactis) | MGG_04400 (Magnaporthe oryzae) | NCU07420 (Neurospora crassa) | TIF1 (Saccharomyces cerevisiae) | tif1 (Schizosaccharomyces pombe) | TIF2 (Saccharomyces cerevisiae) | TIF4A-3 (Arabidopsis thaliana) |
Ageing Relevance Analysis |
: |
Observation Type |
Count |
Ageing Relevance |
Source |
Ageing Phenotype Observation—Data Type 1 |
1 |
yes (Exp. Analysis) |
GenAge |
Ageing Phenotype Observation—Data Type 2 Lifespan Effect |
|
|
|
increased |
1 |
yes (Exp. Analysis) |
Lifespan Observations Database |
Homology Analysis |
1 |
- (basis for a Comp. Analysis) putative (Comp. Analysis) |
AgeFactDB Homology Analysis |
Total |
3 |
|
|
|
Ageing Factor Stable ID |
: |
AF_008668 |
Download |
: |
XML |
Protein Information
no protein information available
Observations
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
# |
Observation Stable ID |
Homology Group Genes |
#EGHG |
Description |
Source |
Homology Source |
1 |
OB_008378 |
|
2 |
The HomoloGene homology group 103998 contains 2 genes with experimental evidence for ageing relevance (TIF1 - Saccharomyces cerevisiae | TIF2 - Saccharomyces cerevisiae) and 15 other genes. |
AgeFactDB Homology Analysis |
HomoloGene homology group 103998 |
Sequences
no sequence information available
References
MeSH Terms:
Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms.
They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page.
MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Smith ED, Tsuchiya M, Fox LA, Dang N, Hu D, Kerr EO, Johnston ED, Tchao BN, Pak DN, Welton KL, Promislow DE, Thomas JH, Kaeberlein M, Kennedy BK:
Quantitative evidence for conserved longevity pathways between divergent eukaryotic species.
Genome Res. 2008; 18: 564-70.
PubMed (ID: 18340043), PubMed Central (ID: PMC2279244), doi:10.1101/gr.074724.107
MeSH Terms: Caenorhabditis elegans/genetics; Longevity/genetics; Saccharomyces cerevisiae/genetics
- Managbanag JR, Witten TM, Bonchev D, Fox LA, Tsuchiya M, Kennedy BK, Kaeberlein M:
Shortest-path network analysis is a useful approach toward identifying genetic determinants of longevity.
PLoS ONE. 2008; 3: e3802.
PubMed (ID: 19030232), PubMed Central (ID: PMC2583956), doi:10.1371/journal.pone.0003802
MeSH Terms: Cell Physiological Phenomena/genetics; Gene Regulatory Networks; Saccharomyces cerevisiae/cytology; Saccharomyces cerevisiae/genetics
- Laschober GT, Ruli D, Hofer E, Muck C, Carmona-Gutierrez D, Ring J, Hutter E, Ruckenstuhl C, Micutkova L, Brunauer R, Jamnig A, Trimmel D, Herndler-Brandstetter D, Brunner S, Zenzmaier C, Sampson N, Breitenbach M, Fröhlich KU, Grubeck-Loebenstein B, Berger P, Wieser M, Grillari-Voglauer R, Thallinger GG, Grillari J, Trajanoski Z, Madeo F, Lepperdinger G, Jansen-Dürr P:
Identification of evolutionarily conserved genetic regulators of cellular aging.
Aging Cell. 2010; 9: 1084-97.
PubMed (ID: 20883526), PubMed Central (ID: PMC2997327), doi:10.1111/j.1474-9726.2010.00637.x
MeSH Terms: Cell Aging/genetics; Evolution, Molecular; Gene Expression Regulation
Sources
Ageing-related Data Sources
Additional Data Sources