Gene: RPL29 - Saccharomyces cerevisiae
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Gene Symbol | : | RPL29 | ||||||||||||||||||||||||
NCBI Gene ID | : | 850592 | ||||||||||||||||||||||||
Species | : | Saccharomyces cerevisiae | ||||||||||||||||||||||||
Gene Synonyms | : | |||||||||||||||||||||||||
Gene Homologs | : | AGOS_ADL125C (Eremothecium gossypii) | KLLA0D16071g (Kluyveromyces lactis) | MGG_06333 (Magnaporthe oryzae) | NCU00315 (Neurospora crassa) | RPL29 (Saccharomyces cerevisiae) | ||||||||||||||||||||||||
Ageing Relevance Analysis | : |
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Ageing Factor Stable ID | : | AF_008680 | ||||||||||||||||||||||||
Download | : | XML |
Protein Information
no protein information available
Observations
Ageing Phenotype
Data Type 1
no ageing phenotype observation—data type 1 available
Data Type 2
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Organism | Ageing Factor | Lifespan Observation | Reference | |||||||||||||||||||||||||||||||||||||||
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# | Observation Stable ID | Species | Strain | Gene | Compound | Other Ageing Factor | Significant Lifespan Effect | Change | Observed Lifespan | Reference Lifespan | Lifespan Unit | Measure | Temperature | Temperature Unit | Sex/Mating Type | Description | Author | Year | PubMed | DOI | Source | |||||||||||||||||||||
1 | OB_000467 | Saccharomyces cerevisiae | BY4741 |
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increased | 35.47% | 30.075 | 22.2 | divisions | mean | 30 | ℃ | mata | Supplemental Data Table | Steffen et al. | 2008 | 18423200 | doi:10.1016/j.cell.2008.02.037 | Lifespan Observations Database (ID: 1731) | |||||||||||||||||||||||
2 | OB_007534 | Saccharomyces cerevisiae |
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increased | 35.00% | unknown | Replicative lifespan increased by 20%-35% in the alpha and a strains | Steffen et al. | 2008 | 18423200 | doi:10.1016/j.cell.2008.02.037 | GenAge | ||||||||||||||||||||||||||||||
3 | OB_000269 | Saccharomyces cerevisiae | BY4742 |
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increased | 28.26% | 35.4 | 27.6 | divisions | mean | 30 | ℃ | matalpha | Deletion of GCN4 prevents maximal life span extension from deletion of ribosomal protein genes coding for proteins in the large ribosomal subunit. From Supplemental Figure 5. | Steffen et al. | 2008 | 18423200 | doi:10.1016/j.cell.2008.02.037 | Lifespan Observations Database (ID: 1275) | |||||||||||||||||||||||
4 | OB_000268 | Saccharomyces cerevisiae | BY4742 |
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increased | 26.09% | 34.8 | 27.6 | divisions | mean | 30 | ℃ | matalpha | Deletion of GCN4 prevents maximal life span extension from deletion of ribosomal protein genes coding for proteins in the large ribosomal subunit. From Supplemental Figure 5. | Steffen et al. | 2008 | 18423200 | doi:10.1016/j.cell.2008.02.037 | Lifespan Observations Database (ID: 1274) | |||||||||||||||||||||||
5 | OB_000352 | Saccharomyces cerevisiae | BY4742 |
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increased | 22.82% | 30.32 | 24.6857 | divisions | mean | 30 | ℃ | matalpha | Supplemental Data Table | Steffen et al. | 2008 | 18423200 | doi:10.1016/j.cell.2008.02.037 | Lifespan Observations Database (ID: 1628) | |||||||||||||||||||||||
6 | OB_000238 | Saccharomyces cerevisiae | BY4742 |
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increased | 21.77% | 30.2 | 24.8 | divisions | mean | 30 | ℃ | matalpha | Deletion of several individual ribosomal protein genes that code for components of the large ribosomal subunit increase replicative life span. | Steffen et al. | 2008 | 18423200 | doi:10.1016/j.cell.2008.02.037 | Lifespan Observations Database (ID: 1241) |
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:
- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
# | Observation Stable ID | Homology Group Genes | #EGHG | Description | Source | Homology Source | ||||||||||||||||||
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1 | OB_008208 |
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1 | The HomoloGene homology group 41938 contains 1 gene with experimental evidence for ageing relevance (RPL29 - Saccharomyces cerevisiae) and 4 other genes. | AgeFactDB Homology Analysis | HomoloGene homology group 41938 |
Sequences
no sequence information available
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Steffen KK, MacKay VL, Kerr EO, Tsuchiya M, Hu D, Fox LA, Dang N, Johnston ED, Oakes JA, Tchao BN, Pak DN, Fields S, Kennedy BK, Kaeberlein M:
Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4.
Cell. 2008; 133: 292-302.
PubMed (ID: 18423200), PubMed Central (ID: PMC2749658), doi:10.1016/j.cell.2008.02.037
MeSH Terms: DNA-Binding Proteins/physiology; Ribosome Subunits, Large, Eukaryotic/physiology; Saccharomyces cerevisiae Proteins/physiology; Saccharomyces cerevisiae/physiology; Transcription Factors/physiology
Sources
Ageing-related Data Sources
- AgeFactDB Homology Analysis
- GenAge
- Lifespan Observations Database
Additional Data Sources
- AgeFactDB Pipeline
- HomoloGene
- NCBI Taxonomy
- PubMed