Gene: RAD51 - Saccharomyces cerevisiae
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Gene Symbol | : | RAD51 | ||||||||||||||||||||||||
NCBI Gene ID | : | 856831 | ||||||||||||||||||||||||
Species | : | Saccharomyces cerevisiae | ||||||||||||||||||||||||
Gene Synonyms | : | |||||||||||||||||||||||||
Gene Homologs | : | AGOS_ACR226W (Eremothecium gossypii) | KLLA0E20241g (Kluyveromyces lactis) | LOC708579 (Macaca mulatta) | MGG_11350 (Magnaporthe oryzae) | NCU02741 (Neurospora crassa) | Os11g0615800 (Oryza sativa) | Os12g0497300 (Oryza sativa) | rad-51 (Caenorhabditis elegans) | RAD51 (Arabidopsis thaliana) | RAD51 (Bos taurus) | RAD51 (Canis lupus familiaris) | rad51 (Danio rerio) | RAD51 (Gallus gallus) | RAD51 (Homo sapiens) | Rad51 (Mus musculus) | RAD51 (Pan troglodytes) | Rad51 (Rattus norvegicus) | RAD51 (Saccharomyces cerevisiae) | rhp51 (Schizosaccharomyces pombe) | spn-A (Drosophila melanogaster) | ||||||||||||||||||||||||
Ageing Relevance Analysis | : |
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Ageing Factor Stable ID | : | AF_008740 | ||||||||||||||||||||||||
Download | : | XML |
Protein Information
no protein information available
Observations
Ageing Phenotype
Data Type 1
no ageing phenotype observation—data type 1 available
Data Type 2
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Organism | Ageing Factor | Lifespan Observation | Reference | ||||||||||||||||||||||||||||||||
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# | Observation Stable ID | Species | Strain | Gene | Compound | Other Ageing Factor | Significant Lifespan Effect | Change | Observed Lifespan | Reference Lifespan | Lifespan Unit | Measure | Temperature | Temperature Unit | Sex/Mating Type | Description | Author | Year | PubMed | DOI | Source | ||||||||||||||
1 | OB_005776 | Saccharomyces cerevisiae |
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decreased | -40.00% | unknown | Mutations result in a 40% reduced lifespan. | Park et al. | 1999 | 10207108 | GenAge | ||||||||||||||||||||||||
2 | OB_000539 | Saccharomyces cerevisiae | PSY316 |
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decreased | -43.48% | 13 | 23 | 30 | ℃ | matalpha | Deletion causes a 40% reduction in mean life span in strain PSY316. Other phenotypes: Rad51p is required for gene conversion, but not for repair of an HO-induced double-strand break [ 8692957]. Deletion of rad51 decreases formation of extrachromosomal rDNA circles [ 10207108]. | Park et al. | 1999 | 10207108 | Lifespan Observations Database (ID: 17) |
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:
- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
Sequences
no sequence information available
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Park PU, Defossez PA, Guarente L:
Effects of mutations in DNA repair genes on formation of ribosomal DNA circles and life span in Saccharomyces cerevisiae.
Mol Cell Biol. 1999; 19: 3848-56.
PubMed (ID: 10207108), PubMed Central (ID: PMC84236)
MeSH Terms: Cell Aging/genetics; DNA Repair/genetics; DNA, Circular/genetics; DNA, Ribosomal/genetics; Saccharomyces cerevisiae/genetics; Silent Information Regulator Proteins, Saccharomyces cerevisiae
Sources
Ageing-related Data Sources
- AgeFactDB Homology Analysis
- GenAge
- Lifespan Observations Database
Additional Data Sources
- AgeFactDB Pipeline
- HomoloGene
- NCBI Taxonomy
- PubMed