Gene: SIP1 - Saccharomyces cerevisiae
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Gene Symbol | : | SIP1 | ||||||||||||||||||||||||
NCBI Gene ID | : | 852032 | ||||||||||||||||||||||||
Species | : | Saccharomyces cerevisiae | ||||||||||||||||||||||||
Gene Synonyms | : | |||||||||||||||||||||||||
Gene Homologs | : | AGOS_ADR194C (Eremothecium gossypii) | SIP1 (Saccharomyces cerevisiae) | ||||||||||||||||||||||||
Ageing Relevance Analysis | : |
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Ageing Factor Stable ID | : | AF_008880 | ||||||||||||||||||||||||
Download | : | XML |
Protein Information
no protein information available
Observations
Ageing Phenotype
Data Type 1
no ageing phenotype observation—data type 1 available
Data Type 2
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Organism | Ageing Factor | Lifespan Observation | Reference | ||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
# | Observation Stable ID | Species | Strain | Gene | Compound | Other Ageing Factor | Significant Lifespan Effect | Change | Observed Lifespan | Reference Lifespan | Lifespan Unit | Measure | Temperature | Temperature Unit | Sex/Mating Type | Description | Author | Year | PubMed | DOI | Source | ||||||||||||||
1 | OB_002111 | Saccharomyces cerevisiae | YB332 |
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decreased | -18.00% | divisions | mean | 30 | ℃ | mata | Deletion reduces life span without accompanying aging biomarkers. | Ashrafi et al. | 2000 | 10921902 | Lifespan Observations Database (ID: 33) | |||||||||||||||||||
2 | OB_007021 | Saccharomyces cerevisiae |
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decreased | -80.00% | unknown | Replicative lifespan decreased by 80% | Ashrafi et al. | 2000 | 10921902 | GenAge | ||||||||||||||||||||||||
3 | OB_007022 | Saccharomyces cerevisiae |
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increased | unknown | Mean chronological lifespan increased in the a strain | Matecic et al. | 2010 | 20421943 | doi:10.1371/journal.pgen.1000921 | GenAge |
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:
- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
# | Observation Stable ID | Homology Group Genes | #EGHG | Description | Source | Homology Source | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | OB_008206 |
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1 | The HomoloGene homology group 38824 contains 1 gene with experimental evidence for ageing relevance (SIP1 - Saccharomyces cerevisiae) and 1 other gene. | AgeFactDB Homology Analysis | HomoloGene homology group 38824 |
Sequences
no sequence information available
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Ashrafi K, Lin SS, Manchester JK, Gordon JI:
Sip2p and its partner snf1p kinase affect aging in S. cerevisiae.
Genes Dev. 2000; 14: 1872-85.
PubMed (ID: 10921902), PubMed Central (ID: PMC316829)
MeSH Terms: DNA-Binding Proteins/metabolism; Fungal Proteins/metabolism; Protein-Serine-Threonine Kinases/metabolism; Repressor Proteins/metabolism; Saccharomyces cerevisiae Proteins; Saccharomyces cerevisiae/physiology; Trans-Activators - Matecic M, Smith DL, Pan X, Maqani N, Bekiranov S, Boeke JD, Smith JS:
A microarray-based genetic screen for yeast chronological aging factors.
PLoS Genet. 2010; 6: e1000921.
PubMed (ID: 20421943), PubMed Central (ID: PMC2858703), doi:10.1371/journal.pgen.1000921
MeSH Terms: Oligonucleotide Array Sequence Analysis; Saccharomyces cerevisiae/genetics; Saccharomyces cerevisiae/physiology
Sources
Ageing-related Data Sources
- AgeFactDB Homology Analysis
- GenAge
- Lifespan Observations Database
Additional Data Sources
- AgeFactDB Pipeline
- HomoloGene
- NCBI Taxonomy
- PubMed