Gene: hsp-16.49 - Caenorhabditis elegans
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Gene Symbol | : | hsp-16.49 | ||||||||||||||||||||||||
NCBI Gene ID | : | 179288 | ||||||||||||||||||||||||
Species | : | Caenorhabditis elegans | ||||||||||||||||||||||||
Gene Synonyms | : | |||||||||||||||||||||||||
Gene Homologs | : | F08H9.3 (Caenorhabditis elegans) | F08H9.4 (Caenorhabditis elegans) | hsp-16.1 (Caenorhabditis elegans) | hsp-16.11 (Caenorhabditis elegans) | hsp-16.2 (Caenorhabditis elegans) | hsp-16.41 (Caenorhabditis elegans) | hsp-16.48 (Caenorhabditis elegans) | hsp-16.49 (Caenorhabditis elegans) | sip-1 (Caenorhabditis elegans) | ||||||||||||||||||||||||
Ageing Relevance Analysis | : |
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Ageing Factor Stable ID | : | AF_009010 | ||||||||||||||||||||||||
Download | : | XML |
Protein Information
Protein Name | Species | UniProt Accession Number | UniProt Entry Name | Protein Function | Sequence |
---|---|---|---|---|---|
Heat shock protein Hsp-16.48/Hsp-16.49 | Caenorhabditis elegans | P02513 (UniProtKB/Swiss-Prot) | HSP17_CAEEL (UniProtKB/Swiss-Prot) | View |
Observations
Ageing Phenotype
Data Type 1
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
# | Observation Stable ID | Species | Gene | Other Ageing Factor | Description | PubMed | Source | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
1 | OB_007910 | Caenorhabditis elegans |
|
Overexpression enhanced stress resistance and extended lifespan. | 12882326 | GenAge |
Data Type 2
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Organism | Ageing Factor | Lifespan Observation | Reference | ||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
# | Observation Stable ID | Species | Strain | Gene | Compound | Other Ageing Factor | Significant Lifespan Effect | Change | Observed Lifespan | Reference Lifespan | Lifespan Unit | Measure | Temperature | Temperature Unit | Sex/Mating Type | Description | Author | Year | PubMed | DOI | Source | ||||||||||||||
1 | OB_003810 | Caenorhabditis elegans |
|
increased | Overexpression enhanced extended lifespan. Other phenotypes: Enhanced stress resistance. | Walker et al. | 2003 | 12882326 | Lifespan Observations Database (ID: 541) | ||||||||||||||||||||||||||
2 | OB_007911 | Caenorhabditis elegans |
|
increased | unknown | Overexpression enhanced stress resistance and extended lifespan. | Walker et al. | 2003 | 12882326 | GenAge |
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:
- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
# | Observation Stable ID | Homology Group Genes | #EGHG | Description | Source | Homology Source |
---|---|---|---|---|---|---|
1 | OB_008196 | 3 | The HomoloGene homology group 43554 contains 3 genes with experimental evidence for ageing relevance (hsp-16.1 - Caenorhabditis elegans | hsp-16.48 - Caenorhabditis elegans | hsp-16.49 - Caenorhabditis elegans) and 6 other genes. | AgeFactDB Homology Analysis | HomoloGene homology group 43554 |
Sequences
HSP17_CAEEL | P02513 | Heat shock protein Hsp-16.48/Hsp-16.49 (Caenorhabditis elegans) from UniProtKB/Swiss-Prot Length: 143 10 20 30 40 50 60 70 80 90 100 110 120 130 140 HSP17_CAEEL 1 MLMLRSPFSDSNVLDHFLDEITGSVQFPYWRNADHNSFNFSDNIGEIVNDESKFSVQLDVSHFKPEDLKIELDGRELKIEGIQEKKSEHGYSKRSFSKMILLPEDVDLTSVKSAISNEGKLQIEAPKKTNSSRSIPINFVAKH 143
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Walker GA, Lithgow GJ:
Lifespan extension in C. elegans by a molecular chaperone dependent upon insulin-like signals.
Aging Cell. 2003; 2: 131-9.
PubMed (ID: 12882326)
MeSH Terms: Caenorhabditis elegans Proteins/physiology; Caenorhabditis elegans/physiology; Longevity/physiology; Signal Transduction/physiology; Transcription Factors/physiology
Sources
Ageing-related Data Sources
- AgeFactDB Curator
- AgeFactDB Homology Analysis
- GenAge
- Lifespan Observations Database
Additional Data Sources
- AgeFactDB Pipeline
- HomoloGene
- NCBI Taxonomy
- PubMed
- UniProtKB/Swiss-Prot