1 |
OB_001000 |
Caenorhabditis elegans |
N2 |
Gene Symbol |
Species |
NCBI Gene ID |
Allele Type |
Allele Name |
Reference Allele Type |
Allele Change |
daf-9 |
Caenorhabditis elegans |
180889 |
unknown |
rh50 |
unknown |
unknown |
|
Compound Name |
Quantity |
Quantity Unit |
Dafachronic acid |
0 |
- |
|
Other Ageing Factor Name |
Additional Information |
Germ cell ablation |
Z2, Z3 laser ablation at L1 larval stage |
|
increased |
23.46% |
20 |
16.2 |
days |
mean |
20 |
℃ |
hermaphrodite |
When germline-deficient animals lacking somatic reproductive tissues are given dafachronic acid, their expression of DAF-12/NHR-dependent target genes is restored and their lifespan is increased. |
Yamawaki et al. |
2010 |
20824162 |
doi:10.1371/journal.pbio.1000468 |
Lifespan Observations Database (ID: 2318) |
2 |
OB_004352 |
Caenorhabditis elegans |
N2 |
|
Compound Name |
Quantity |
Quantity Unit |
Dafachronic acid |
0 |
- |
|
Other Ageing Factor Name |
Additional Information |
Germ cell ablation |
Z2, Z3 laser ablation at L1 larval stage |
Somatic gonad ablation |
Z1, Z4 laser ablation at L1 larval stage |
|
increased |
22.84% |
19.9 |
16.2 |
days |
mean |
20 |
℃ |
hermaphrodite |
When germline-deficient animals lacking somatic reproductive tissues are given dafachronic acid, their expression of DAF-12/NHR-dependent target genes is restored and their lifespan is increased. |
Yamawaki et al. |
2010 |
20824162 |
doi:10.1371/journal.pbio.1000468 |
Lifespan Observations Database (ID: 2314) |
3 |
OB_004349 |
Caenorhabditis elegans |
N2 |
|
Compound Name |
Quantity |
Quantity Unit |
Dafachronic acid |
0 |
- |
|
Other Ageing Factor Name |
Additional Information |
Germ cell ablation |
Z2,Z3 laser ablation at L1 larval stage |
|
increased |
19.79% |
22.4 |
18.7 |
days |
mean |
20 |
℃ |
hermaphrodite |
When germline-deficient animals lacking somatic reproductive tissues are given dafachronic acid, their expression of DAF-12/NHR-dependent target genes is restored and their lifespan is increased. |
Yamawaki et al. |
2010 |
20824162 |
doi:10.1371/journal.pbio.1000468 |
Lifespan Observations Database (ID: 2305) |
4 |
OB_004351 |
Caenorhabditis elegans |
N2 |
|
Compound Name |
Quantity |
Quantity Unit |
Dafachronic acid |
0 |
- |
|
Other Ageing Factor Name |
Additional Information |
Germ cell ablation |
Z2, Z3 laser ablation at L1 larval stage |
|
increased |
17.90% |
19.1 |
16.2 |
days |
mean |
20 |
℃ |
hermaphrodite |
When germline-deficient animals lacking somatic reproductive tissues are given dafachronic acid, their expression of DAF-12/NHR-dependent target genes is restored and their lifespan is increased. |
Yamawaki et al. |
2010 |
20824162 |
doi:10.1371/journal.pbio.1000468 |
Lifespan Observations Database (ID: 2313) |
5 |
OB_001007 |
Caenorhabditis elegans |
N2 |
Gene Symbol |
Species |
NCBI Gene ID |
Allele Type |
Allele Name |
Reference Allele Type |
Allele Change |
daf-12 |
Caenorhabditis elegans |
181263 |
unknown |
rh61rh411 |
unknown |
unknown |
|
Compound Name |
Quantity |
Quantity Unit |
Dafachronic acid |
0 |
- |
|
Other Ageing Factor Name |
Additional Information |
Germ cell ablation |
Z2, Z3 laser ablation at L1 larval stage |
Somatic gonad ablation |
Z1, Z4 laser ablation at L1 larval stage |
|
increased |
13.61% |
16.7 |
14.7 |
days |
mean |
20 |
℃ |
hermaphrodite |
When germline-deficient animals lacking somatic reproductive tissues are given dafachronic acid, their expression of DAF-12/NHR-dependent target genes is restored and their lifespan is increased. |
Yamawaki et al. |
2010 |
20824162 |
doi:10.1371/journal.pbio.1000468 |
Lifespan Observations Database (ID: 2325) |
6 |
OB_004354 |
Caenorhabditis elegans |
N2 |
|
Compound Name |
Quantity |
Quantity Unit |
Dafachronic acid |
0 |
- |
|
Other Ageing Factor Name |
Additional Information |
Germ cell ablation |
Z2, Z3 laser ablation at L1 larval stage |
|
increased |
12.90% |
17.5 |
15.5 |
days |
mean |
20 |
℃ |
hermaphrodite |
When germline-deficient animals lacking somatic reproductive tissues are given dafachronic acid, their expression of DAF-12/NHR-dependent target genes is restored and their lifespan is increased. |
Yamawaki et al. |
2010 |
20824162 |
doi:10.1371/journal.pbio.1000468 |
Lifespan Observations Database (ID: 2329) |
7 |
OB_004350 |
Caenorhabditis elegans |
N2 |
|
Compound Name |
Quantity |
Quantity Unit |
Dafachronic acid |
0 |
- |
|
Other Ageing Factor Name |
Additional Information |
Germ cell ablation |
Z2,Z3 laser ablation at L1 larval stage |
Somatic gonad ablation |
Z1,Z4 laser ablation at L1 larval stage |
|
increased |
11.76% |
20.9 |
18.7 |
days |
mean |
20 |
℃ |
hermaphrodite |
When germline-deficient animals lacking somatic reproductive tissues are given dafachronic acid, their expression of DAF-12/NHR-dependent target genes is restored and their lifespan is increased. |
Yamawaki et al. |
2010 |
20824162 |
doi:10.1371/journal.pbio.1000468 |
Lifespan Observations Database (ID: 2306) |
8 |
OB_004355 |
Caenorhabditis elegans |
N2 |
|
Compound Name |
Quantity |
Quantity Unit |
Dafachronic acid |
0 |
- |
|
Other Ageing Factor Name |
Additional Information |
Germ cell ablation |
Z2, Z3 laser ablation at L1 larval stage |
Somatic gonad ablation |
Z1, Z4 laser ablation at L1 larval stage |
|
increased |
7.74% |
16.7 |
15.5 |
days |
mean |
20 |
℃ |
hermaphrodite |
When germline-deficient animals lacking somatic reproductive tissues are given dafachronic acid, their expression of DAF-12/NHR-dependent target genes is restored and their lifespan is increased. |
Yamawaki et al. |
2010 |
20824162 |
doi:10.1371/journal.pbio.1000468 |
Lifespan Observations Database (ID: 2330) |
9 |
OB_000997 |
Caenorhabditis elegans |
N2 |
Gene Symbol |
Species |
NCBI Gene ID |
Allele Type |
Allele Name |
Reference Allele Type |
Allele Change |
daf-9 |
Caenorhabditis elegans |
180889 |
unknown |
rh50 |
unknown |
unknown |
|
Compound Name |
Quantity |
Quantity Unit |
Dafachronic acid |
0 |
- |
|
Other Ageing Factor Name |
Additional Information |
Germ cell ablation |
Z2, Z3 laser ablation at L1 larval stage |
|
increased |
6.95% |
20 |
18.7 |
days |
mean |
20 |
℃ |
hermaphrodite |
When germline-deficient animals lacking somatic reproductive tissues are given dafachronic acid, their expression of DAF-12/NHR-dependent target genes is restored and their lifespan is increased. |
Yamawaki et al. |
2010 |
20824162 |
doi:10.1371/journal.pbio.1000468 |
Lifespan Observations Database (ID: 2311) |
10 |
OB_004353 |
Caenorhabditis elegans |
N2 |
|
Compound Name |
Quantity |
Quantity Unit |
Dafachronic acid |
0 |
- |
|
|
none |
0.00% |
15.5 |
15.5 |
days |
mean |
20 |
℃ |
hermaphrodite |
When germline-deficient animals lacking somatic reproductive tissues are given dafachronic acid, their expression of DAF-12/NHR-dependent target genes is restored and their lifespan is increased. |
Yamawaki et al. |
2010 |
20824162 |
doi:10.1371/journal.pbio.1000468 |
Lifespan Observations Database (ID: 2328) |
11 |
OB_001005 |
Caenorhabditis elegans |
N2 |
Gene Symbol |
Species |
NCBI Gene ID |
Allele Type |
Allele Name |
Reference Allele Type |
Allele Change |
daf-12 |
Caenorhabditis elegans |
181263 |
unknown |
rh61rh411 |
unknown |
unknown |
|
Compound Name |
Quantity |
Quantity Unit |
Dafachronic acid |
0 |
- |
|
Other Ageing Factor Name |
Additional Information |
Germ cell ablation |
Z2, Z3 laser ablation at L1 larval stage |
|
none |
-4.08% |
14.1 |
14.7 |
days |
mean |
20 |
℃ |
hermaphrodite |
When germline-deficient animals lacking somatic reproductive tissues are given dafachronic acid, their expression of DAF-12/NHR-dependent target genes is restored and their lifespan is increased. |
Yamawaki et al. |
2010 |
20824162 |
doi:10.1371/journal.pbio.1000468 |
Lifespan Observations Database (ID: 2323) |
12 |
OB_001003 |
Caenorhabditis elegans |
N2 |
Gene Symbol |
Species |
NCBI Gene ID |
Allele Type |
Allele Name |
Reference Allele Type |
Allele Change |
daf-12 |
Caenorhabditis elegans |
181263 |
unknown |
rh61rh411 |
unknown |
unknown |
|
Compound Name |
Quantity |
Quantity Unit |
Dafachronic acid |
0 |
- |
|
|
decreased |
-7.48% |
13.6 |
14.7 |
days |
mean |
20 |
℃ |
hermaphrodite |
When germline-deficient animals lacking somatic reproductive tissues are given dafachronic acid, their expression of DAF-12/NHR-dependent target genes is restored and their lifespan is increased. |
Yamawaki et al. |
2010 |
20824162 |
doi:10.1371/journal.pbio.1000468 |
Lifespan Observations Database (ID: 2320) |
13 |
OB_001010 |
Caenorhabditis elegans |
N2 |
Gene Symbol |
Species |
NCBI Gene ID |
Allele Type |
Allele Name |
Reference Allele Type |
Allele Change |
daf-16 |
Caenorhabditis elegans |
172981 |
deletion / null |
mu86 |
unknown |
unknown |
|
Compound Name |
Quantity |
Quantity Unit |
Dafachronic acid |
0 |
- |
|
|
decreased |
-12.26% |
13.6 |
15.5 |
days |
mean |
20 |
℃ |
hermaphrodite |
When germline-deficient animals lacking somatic reproductive tissues are given dafachronic acid, their expression of DAF-12/NHR-dependent target genes is restored and their lifespan is increased. |
Yamawaki et al. |
2010 |
20824162 |
doi:10.1371/journal.pbio.1000468 |
Lifespan Observations Database (ID: 2332) |
14 |
OB_001012 |
Caenorhabditis elegans |
N2 |
Gene Symbol |
Species |
NCBI Gene ID |
Allele Type |
Allele Name |
Reference Allele Type |
Allele Change |
daf-16 |
Caenorhabditis elegans |
172981 |
deletion / null |
mu86 |
unknown |
unknown |
|
Compound Name |
Quantity |
Quantity Unit |
Dafachronic acid |
0 |
- |
|
Other Ageing Factor Name |
Additional Information |
Germ cell ablation |
Z2, Z3 laser ablation at L1 larval stage |
|
decreased |
-15.48% |
13.1 |
15.5 |
days |
mean |
20 |
℃ |
hermaphrodite |
When germline-deficient animals lacking somatic reproductive tissues are given dafachronic acid, their expression of DAF-12/NHR-dependent target genes is restored and their lifespan is increased. |
Yamawaki et al. |
2010 |
20824162 |
doi:10.1371/journal.pbio.1000468 |
Lifespan Observations Database (ID: 2334) |
15 |
OB_001013 |
Caenorhabditis elegans |
N2 |
Gene Symbol |
Species |
NCBI Gene ID |
Allele Type |
Allele Name |
Reference Allele Type |
Allele Change |
daf-16 |
Caenorhabditis elegans |
172981 |
deletion / null |
mu86 |
unknown |
unknown |
|
Compound Name |
Quantity |
Quantity Unit |
Dafachronic acid |
0 |
- |
|
Other Ageing Factor Name |
Additional Information |
Germ cell ablation |
Z2, Z3 laser ablation at L1 larval stage |
Somatic gonad ablation |
Z1, Z4 laser ablation at L1 larval stage |
|
decreased |
-24.52% |
11.7 |
15.5 |
days |
mean |
20 |
℃ |
hermaphrodite |
When germline-deficient animals lacking somatic reproductive tissues are given dafachronic acid, their expression of DAF-12/NHR-dependent target genes is restored and their lifespan is increased. |
Yamawaki et al. |
2010 |
20824162 |
doi:10.1371/journal.pbio.1000468 |
Lifespan Observations Database (ID: 2335) |