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Compound: 3,5-Dihydroxy-4'-acetoxy-trans-stilbene - Saccharomyces cerevisiae

Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Ageing relevance by experimental analysis: yes
Defined by: Name
Ageing relevance by experimental analysis: yes
Defined by: Name

Summary

Compound Name : 3,5-Dihydroxy-4'-acetoxy-trans-stilbene
Species : Saccharomyces cerevisiae
Ageing Relevance Analysis :
Observation Type Count Ageing Relevance Source
Ageing Phenotype Observation—Data Type 2
Lifespan Effect
increased 1 yes (Exp. Analysis) [Lifespan Observations Database icon]Lifespan Observations Database
Total 1
Ageing Factor Stable ID : AF_009104
Download : [xml icon]XML

Observations

Ageing Phenotype

Data Type 1

no ageing phenotype observation—data type 1 available

Data Type 2

Ageing Relevance:
  • yes (Exp. Analysis)
  • yes, but no ageing factor assigned (Exp. Analysis)
  • no (Exp. Analysis)
  • putative (Comp. Analysis)
Organism Ageing Factor Lifespan Observation Reference
# Observation Stable ID Species Strain Gene Compound Other Ageing Factor Significant Lifespan Effect Change Observed Lifespan Reference Lifespan Lifespan Unit Measure Temperature Temperature Unit Sex/Mating Type Description Author Year PubMed DOI Source
1 OB_004469 Saccharomyces cerevisiae PSY316AT
Compound Name Quantity Quantity Unit
3,5-Dihydroxy-4'-acetoxy-trans-stilbene 10 micromolar
increased 54.51% 36 23.3 divisions mean 30 ℃ matalpha Resveratrol and structurally related compounds increased replicative life span in yeast. Yang et al. 2007 17156081 [DOI icon]doi:10.1111/j.1474-9726.2006.00259.x [Lifespan Observations Database icon]Lifespan Observations Database (ID: 4268)

Homology Analysis

no homology analysis observation available

References

MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.

  1. Yang H, Baur JA, Chen A, Miller C, Adams JK, Kisielewski A, Howitz KT, Zipkin RE, Sinclair DA:
    Design and synthesis of compounds that extend yeast replicative lifespan.
    Aging Cell. 2007; 6: 35-43.
    [PubMed icon]PubMed (ID: 17156081), [PubMed icon]PubMed Central (ID: PMC3545651), [DOI icon]doi:10.1111/j.1474-9726.2006.00259.x
    MeSH Terms: Cell Aging/drug effects; Cell Proliferation/drug effects; Saccharomyces cerevisiae/drug effects; Sirtuins/drug effects; Stilbenes/pharmacology

Sources

Ageing-related Data Sources

Additional Data Sources