Compound: Coenzyme Q10 - Caenorhabditis elegans
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Compound Name | : | Coenzyme Q10 | ||||||||||||||||
Species | : | Caenorhabditis elegans | ||||||||||||||||
Ageing Relevance Analysis | : |
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Ageing Factor Stable ID | : | AF_009134 | ||||||||||||||||
Download | : | XML |
Observations
Ageing Phenotype
Data Type 1
no ageing phenotype observation—data type 1 available
Data Type 2
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Organism | Ageing Factor | Lifespan Observation | Reference | ||||||||||||||||||||||||||||||||||||||
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# | Observation Stable ID | Species | Strain | Gene | Compound | Other Ageing Factor | Significant Lifespan Effect | Change | Observed Lifespan | Reference Lifespan | Lifespan Unit | Measure | Temperature | Temperature Unit | Sex/Mating Type | Description | Author | Year | PubMed | DOI | Source | ||||||||||||||||||||
1 | OB_003733 | Caenorhabditis elegans |
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none | 0.00% | 18.1 | 18.1 | days | mean | 20 | ℃ | Addition of coenzyme Q10 to clk-1 mutants prevents lifespan extension and brings the lifespan back to that of control worms. | Takahashi et al. | 2012 | 22244837 | doi:10.1016/j.exger.2011.12.012 | Lifespan Observations Database (ID: 5249) | |||||||||||||||||||||||
2 | OB_004622 | Caenorhabditis elegans | N2 |
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none | 0.00% | 18.1 | 18.1 | days | mean | 20 | ℃ | Addition of Coenzyme Q10 does not affect lifespan in N2 worms | Takahashi et al. | 2012 | 22244837 | doi:10.1016/j.exger.2011.12.012 | Lifespan Observations Database (ID: 5247) |
Homology Analysis
no homology analysis observation available
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Takahashi M, Ogawara M, Shimizu T, Shirasawa T:
Restoration of the behavioral rates and lifespan in clk-1 mutant nematodes in response to exogenous coenzyme Q(10).
Exp Gerontol. 2012; 47: 276-9.
PubMed (ID: 22244837), doi:10.1016/j.exger.2011.12.012
MeSH Terms: Caenorhabditis elegans Proteins/genetics; Caenorhabditis elegans/drug effects; Longevity/drug effects; Ubiquinone/analogs & derivatives