Compound: Carbenicillin - Caenorhabditis elegans
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Compound Name | : | Carbenicillin | ||||||||||||||||
Species | : | Caenorhabditis elegans | ||||||||||||||||
Ageing Relevance Analysis | : |
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Ageing Factor Stable ID | : | AF_009143 | ||||||||||||||||
Download | : | XML |
Observations
Ageing Phenotype
Data Type 1
no ageing phenotype observation—data type 1 available
Data Type 2
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Organism | Ageing Factor | Lifespan Observation | Reference | |||||||||||||||||||||||||||
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# | Observation Stable ID | Species | Strain | Gene | Compound | Other Ageing Factor | Significant Lifespan Effect | Change | Observed Lifespan | Reference Lifespan | Lifespan Unit | Measure | Temperature | Temperature Unit | Sex/Mating Type | Description | Author | Year | PubMed | DOI | Source | |||||||||
1 | OB_004702 | Caenorhabditis elegans | N2 |
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increased | 23.67% | 29.15 | 23.57 | days | mean | 20 | ℃ | Metformin increased lifespan to a similar degree in the absence (25%) or presence of carbenicillin (24%). Thus, metformin does not increase lifespan by preventing bacterial proliferation. | Cabreiro et al. | 2013 | 23540700 | doi:10.1016/j.cell.2013.02.035 | Lifespan Observations Database (ID: 5386) |
Homology Analysis
no homology analysis observation available
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Cabreiro F, Au C, Leung KY, Vergara-Irigaray N, Cochemé HM, Noori T, Weinkove D, Schuster E, Greene ND, Gems D:
Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism.
Cell. 2013; 153: 228-39.
PubMed (ID: 23540700), doi:10.1016/j.cell.2013.02.035
MeSH Terms: Caenorhabditis elegans/drug effects; Caenorhabditis elegans/microbiology; Folic Acid/metabolism; Hypoglycemic Agents/pharmacology; Longevity/drug effects; Metformin/pharmacology; Methionine/metabolism