1 |
OB_004740 |
Saccharomyces cerevisiae |
PSY316AUT |
|
|
Other Ageing Factor Name |
Additional Information |
Dietary restriction |
0.05% glucose |
rho0 |
Absence of mitochondrial DNA. |
|
increased |
133.33% |
28 |
12 |
divisions |
mean |
30 |
℃ |
matalpha |
Dietary restriction at either 0.5% or 0.05% glucose increases the replicative life span of rho0 cells in the PSY316AUT strain background, demonstrating that mitochondrial respiration is not required for life span extension from dietary restriction. |
Kaeberlein et al. |
2005 |
16311627 |
doi:10.1371/journal.pgen.0010069 |
Lifespan Observations Database (ID: 1115) |
2 |
OB_004739 |
Saccharomyces cerevisiae |
PSY316AUT |
|
|
Other Ageing Factor Name |
Additional Information |
Dietary restriction |
0.5% glucose |
rho0 |
Absence of mitochondrial DNA. |
|
increased |
83.33% |
22 |
12 |
divisions |
mean |
30 |
℃ |
matalpha |
Dietary restriction at either 0.5% or 0.05% glucose increases the replicative life span of rho0 cells in the PSY316AUT strain background, demonstrating that mitochondrial respiration is not required for life span extension from dietary restriction. |
Kaeberlein et al. |
2005 |
16311627 |
doi:10.1371/journal.pgen.0010069 |
Lifespan Observations Database (ID: 1114) |
3 |
OB_004733 |
Saccharomyces cerevisiae |
BY4742 |
|
|
Other Ageing Factor Name |
Additional Information |
Dietary restriction |
0.05% glucose |
rho0 |
Absence of mitochondrial DNA. |
|
increased |
29.49% |
30.3 |
23.4 |
divisions |
mean |
30 |
℃ |
matalpha |
The replicative life span of rho0 cells does not differ significantly from that of wild type mother cells in the BY4742 strain background. Dietary restriction still increases the life span of BY4742 rho0 cells, demonstrating that mitochondrial respiration is not required for life span extension from dietary restriction in yeast. |
Kaeberlein et al. |
2005 |
16311627 |
doi:10.1371/journal.pgen.0010069 |
Lifespan Observations Database (ID: 1102) |
4 |
OB_004736 |
Saccharomyces cerevisiae |
PSY316AUT |
|
|
Other Ageing Factor Name |
Additional Information |
Dietary restriction |
0.05% glucose |
rho0 |
Absence of mitochondrial DNA. |
|
increased |
22.07% |
27.1 |
22.2 |
divisions |
mean |
30 |
℃ |
matalpha |
The replicative life span of rho0 cells is significantly shorter than wild type mother cells in the PSY316AUT strain background. Dietary restriction still increases the life span of PSY316AUT rho0 cells, demonstrating that mitochondrial respiration is not required for life span extension from dietary restriction in yeast. |
Kaeberlein et al. |
2005 |
16311627 |
doi:10.1371/journal.pgen.0010069 |
Lifespan Observations Database (ID: 1105) |
5 |
OB_000103 |
Saccharomyces cerevisiae |
PSY316AUT |
Gene Symbol |
Species |
NCBI Gene ID |
Allele Type |
Allele Name |
Reference Allele Type |
Allele Change |
CYT1 |
Saccharomyces cerevisiae |
854231 |
deletion / null |
- |
unknown |
unknown |
|
|
Other Ageing Factor Name |
Additional Information |
Dietary restriction |
0.05% glucose |
rho0 |
Absence of mitochondrial DNA. |
|
increased |
14.62% |
24.3 |
21.2 |
divisions |
mean |
30 |
℃ |
matalpha |
PSY316AUT rho0 cells also deleted for CYT1 are short-lived, but still have their life span extended by dietary restriction. These data demonstrate that mitochondrial respiration is not required for life span extension from dietary restriction in the PSY316AUT strain background. |
Kaeberlein et al. |
2005 |
16311627 |
doi:10.1371/journal.pgen.0010069 |
Lifespan Observations Database (ID: 1111) |
6 |
OB_004732 |
Saccharomyces cerevisiae |
BY4742 |
|
|
Other Ageing Factor Name |
Additional Information |
rho0 |
Absence of mitochondrial DNA. |
|
none |
3.85% |
24.3 |
23.4 |
divisions |
mean |
30 |
℃ |
matalpha |
The replicative life span of rho0 cells does not differ significantly from that of wild type mother cells in the BY4742 strain background. Dietary restriction still increases the life span of BY4742 rho0 cells, demonstrating that mitochondrial respiration is not required for life span extension from dietary restriction in yeast. |
Kaeberlein et al. |
2005 |
16311627 |
doi:10.1371/journal.pgen.0010069 |
Lifespan Observations Database (ID: 1101) |
7 |
OB_004735 |
Saccharomyces cerevisiae |
PSY316AUT |
|
|
Other Ageing Factor Name |
Additional Information |
rho0 |
Absence of mitochondrial DNA. |
|
decreased |
-42.79% |
12.7 |
22.2 |
divisions |
mean |
30 |
℃ |
matalpha |
The replicative life span of rho0 cells is significantly shorter than wild type mother cells in the PSY316AUT strain background. Dietary restriction still increases the life span of PSY316AUT rho0 cells, demonstrating that mitochondrial respiration is not required for life span extension from dietary restriction in yeast. |
Kaeberlein et al. |
2005 |
16311627 |
doi:10.1371/journal.pgen.0010069 |
Lifespan Observations Database (ID: 1104) |
8 |
OB_000102 |
Saccharomyces cerevisiae |
PSY316AUT |
Gene Symbol |
Species |
NCBI Gene ID |
Allele Type |
Allele Name |
Reference Allele Type |
Allele Change |
CYT1 |
Saccharomyces cerevisiae |
854231 |
deletion / null |
- |
unknown |
unknown |
|
|
Other Ageing Factor Name |
Additional Information |
rho0 |
Absence of mitochondrial DNA. |
|
decreased |
-45.28% |
11.6 |
21.2 |
divisions |
mean |
30 |
℃ |
matalpha |
PSY316AUT rho0 cells also deleted for CYT1 are short-lived, but still have their life span extended by dietary restriction. These data demonstrate that mitochondrial respiration is not required for life span extension from dietary restriction in the PSY316AUT strain background. |
Kaeberlein et al. |
2005 |
16311627 |
doi:10.1371/journal.pgen.0010069 |
Lifespan Observations Database (ID: 1110) |
9 |
OB_002663 |
Saccharomyces cerevisiae |
BY4741 |
Gene Symbol |
Species |
NCBI Gene ID |
Allele Type |
Allele Name |
Reference Allele Type |
Allele Change |
YNT100 |
Saccharomyces cerevisiae |
|
loss of function |
ynt100-1 |
unknown |
unknown |
|
|
Other Ageing Factor Name |
Additional Information |
rho0 |
Absence of mitochondrial DNA |
|
decreased |
-80.00% |
2 |
10 |
days |
median |
30 |
℃ |
mata |
The translocation of mtDNA fragments to the nucleus correlates with yeast chronological lifespan. |
Cheng et al. |
2010 |
20626726 |
doi:10.1111/j.1474-9726.2010.00607.x |
Lifespan Observations Database (ID: 3955) |
10 |
OB_002664 |
Saccharomyces cerevisiae |
BY4741 |
Gene Symbol |
Species |
NCBI Gene ID |
Allele Type |
Allele Name |
Reference Allele Type |
Allele Change |
YME2 |
Saccharomyces cerevisiae |
855348 |
loss of function |
yme2-1 |
unknown |
unknown |
|
|
Other Ageing Factor Name |
Additional Information |
rho0 |
Absence of mitochondrial DNA |
|
decreased |
-80.00% |
2 |
10 |
days |
median |
30 |
℃ |
mata |
The translocation of mtDNA fragments to the nucleus correlates with yeast chronological lifespan. |
Cheng et al. |
2010 |
20626726 |
doi:10.1111/j.1474-9726.2010.00607.x |
Lifespan Observations Database (ID: 3956) |
11 |
OB_002665 |
Saccharomyces cerevisiae |
BY4741 |
Gene Symbol |
Species |
NCBI Gene ID |
Allele Type |
Allele Name |
Reference Allele Type |
Allele Change |
YME1 |
Saccharomyces cerevisiae |
856135 |
loss of function |
yme1-1 |
unknown |
unknown |
|
|
Other Ageing Factor Name |
Additional Information |
rho0 |
Absence of mitochondrial DNA |
|
decreased |
-80.00% |
2 |
10 |
days |
median |
30 |
℃ |
mata |
The translocation of mtDNA fragments to the nucleus correlates with yeast chronological lifespan. |
Cheng et al. |
2010 |
20626726 |
doi:10.1111/j.1474-9726.2010.00607.x |
Lifespan Observations Database (ID: 3957) |
12 |
OB_004855 |
Saccharomyces cerevisiae |
BY4741 |
|
|
Other Ageing Factor Name |
Additional Information |
rho0 |
Absence of mitochondrial DNA |
|
decreased |
-80.00% |
2 |
10 |
days |
median |
30 |
℃ |
mata |
The translocation of mtDNA fragments to the nucleus correlates with yeast chronological lifespan. |
Cheng et al. |
2010 |
20626726 |
doi:10.1111/j.1474-9726.2010.00607.x |
Lifespan Observations Database (ID: 3954) |