Other Ageing Factor: Stachys lavandulifolia extract - Drosophila melanogaster
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Other Ageing Factor Name | : | Stachys lavandulifolia extract | ||||||||||||||||
Species | : | Drosophila melanogaster | ||||||||||||||||
Ageing Relevance Analysis | : |
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Ageing Factor Stable ID | : | AF_009158 | ||||||||||||||||
Download | : | XML |
Observations
Ageing Phenotype
Data Type 1
no ageing phenotype observation—data type 1 available
Data Type 2
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Organism | Ageing Factor | Lifespan Observation | Reference | ||||||||||||||||||||||
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# | Observation Stable ID | Species | Strain | Gene | Compound | Other Ageing Factor | Significant Lifespan Effect | Change | Observed Lifespan | Reference Lifespan | Lifespan Unit | Measure | Temperature | Temperature Unit | Sex/Mating Type | Description | Author | Year | PubMed | DOI | Source | ||||
1 | OB_004759 | Drosophila melanogaster |
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increased | 55.74% | 49.62 | 31.86 | days | mean | female | Context: Stachyss species have been used as a medicine for centuries throughout the world. Stachys lavandulifolia Vahl. var. lavandulifolia (Lamiaceae) is of interest to researchers because the constituents such as betulinic acid, oleanolic acid, rosmarinic acid, and ursolic acid are similar to other Stachys species commonly used as an alterative in medicinal preparations. Objective: The present study investigated the effects of water extract (SLE(w)) and ethanol extract (SLE(e)) obtained from S. lavandulifolia (SLE) on the longevity of Drosophila melanogaster Meigen. Materials and methods: The effects of different concentrations of SLE (Control+DMSO; 4.0; 12.0 and 20.0 microL/100 mL medium) were administered separately to female and male populations of D. melanogaster for control and SLE groups. Results: In all application groups, each population's longevity increased, depending on the concentration of SLE. The mean life-span of the extract groups which are applied with SLE((w)) was determined to be shorter than the extract groups which are applied with SLE((e)). For example, the maximum mean life-span applied with SLE((w)) increased from 31.86 +/- 0.92 days to 43.21 +/- 1.33 days and the maximum mean life-span applied with SLE((e)) increased from 31.86 +/- 0.92 days to 49.62 +/- 1.62 days in females. Conclusion: These findings demonstrate that the constituents of S. lavandulifolia have great potential as a source for natural health products for D. melanogaster management. | Altun et al. | 2010 | 20738162 | doi:10.3109/13880201003789424 | Lifespan Observations Database (ID: 1869) | |||||||||
2 | OB_004758 | Drosophila melanogaster |
|
increased | 35.62% | 43.21 | 31.86 | days | mean | female | Context: Stachyss species have been used as a medicine for centuries throughout the world. Stachys lavandulifolia Vahl. var. lavandulifolia (Lamiaceae) is of interest to researchers because the constituents such as betulinic acid, oleanolic acid, rosmarinic acid, and ursolic acid are similar to other Stachys species commonly used as an alterative in medicinal preparations. Objective: The present study investigated the effects of water extract (SLE(w)) and ethanol extract (SLE(e)) obtained from S. lavandulifolia (SLE) on the longevity of Drosophila melanogaster Meigen. Materials and methods: The effects of different concentrations of SLE (Control+DMSO; 4.0; 12.0 and 20.0 microL/100 mL medium) were administered separately to female and male populations of D. melanogaster for control and SLE groups. Results: In all application groups, each population's longevity increased, depending on the concentration of SLE. The mean life-span of the extract groups which are applied with SLE((w)) was determined to be shorter than the extract groups which are applied with SLE((e)). For example, the maximum mean life-span applied with SLE((w)) increased from 31.86 +/- 0.92 days to 43.21 +/- 1.33 days and the maximum mean life-span applied with SLE((e)) increased from 31.86 +/- 0.92 days to 49.62 +/- 1.62 days in females. Conclusion: These findings demonstrate that the constituents of S. lavandulifolia have great potential as a source for natural health products for D. melanogaster management. | Altun et al. | 2010 | 20738162 | doi:10.3109/13880201003789424 | Lifespan Observations Database (ID: 1868) |
Homology Analysis
no homology analysis observation available
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Altun D, Ayar A, Uysal H, Kara AA, Unal EL:
Extended longevity of Drosophila melanogaster by water and ethanol extracts of Stachys lavandulifolia.
Pharm Biol. 2010; 48: 1291-6.
PubMed (ID: 20738162), doi:10.3109/13880201003789424
MeSH Terms: Drosophila melanogaster/drug effects; Plant Extracts/pharmacology; Stachys