1 |
OB_004964 |
Caenorhabditis elegans |
eat-2(ad465) |
|
|
Other Ageing Factor Name |
Additional Information |
Food source |
E. coli HB101 has leucine and proline auxotroph phenotype relative to E. coli OP50 has a uracil auxotroph phenotype control. |
|
increased |
76.06% |
25 |
14.2 |
days |
mean |
20 |
℃ |
|
C. elegans eat-2(ad465) mutant fed on HB101 bacterial food source lived approximately 75% longer than OP50 control. |
So et al. |
2011 |
21354440 |
doi:10.1016/j.mad.2011.02.005 |
Lifespan Observations Database (ID: 4985) |
2 |
OB_004965 |
Caenorhabditis elegans |
dbl-1(nk3) |
|
|
Other Ageing Factor Name |
Additional Information |
Food source |
E. coli HB101 has leucine and proline auxotroph phenotype relative to E. coli OP50 has a uracil auxotroph phenotype control. |
|
increased |
49.63% |
20.2 |
13.5 |
days |
mean |
20 |
℃ |
|
C. elegans dbl-1(nk3) mutant fed on HB101 bacterial food source lived approximately 50% longer than OP50 control. |
So et al. |
2011 |
21354440 |
doi:10.1016/j.mad.2011.02.005 |
Lifespan Observations Database (ID: 4986) |
3 |
OB_004966 |
Caenorhabditis elegans |
eat-5(ad1402) |
|
|
Other Ageing Factor Name |
Additional Information |
Food source |
E. coli HB101 has leucine and proline auxotroph phenotype relative to E. coli OP50 has a uracil auxotroph phenotype control. |
|
increased |
35.22% |
21.5 |
15.9 |
days |
mean |
20 |
℃ |
|
C. elegans eat-5(ad1402) mutant fed on HB101 bacterial food source lived approximately 35% longer than OP50 control. |
So et al. |
2011 |
21354440 |
doi:10.1016/j.mad.2011.02.005 |
Lifespan Observations Database (ID: 4987) |
4 |
OB_005001 |
Caenorhabditis elegans |
N2 |
|
|
Other Ageing Factor Name |
Additional Information |
Food source |
Lactobacillus rhamnosus CNCM I-3690 |
|
increased |
20.00% |
18 |
15 |
days |
|
20 |
℃ |
|
Altogether, these results show that, among the 78 LAB strains analyzed; only Lactobacillus rhamnosus CNCM I-3690 strain induced a strong resistance to oxidative stress in C. elegans. |
Grompone et al. |
2012 |
23300685 |
doi:10.1371/journal.pone.0052493 |
Lifespan Observations Database (ID: 5266) |
5 |
OB_004967 |
Caenorhabditis elegans |
daf-2(e1370) |
|
|
Other Ageing Factor Name |
Additional Information |
Food source |
E. coli HB101 has leucine and proline auxotroph phenotype relative to E. coli OP50 has a uracil auxotroph phenotype control. |
|
increased |
19.50% |
38 |
31.8 |
days |
mean |
20 |
℃ |
|
C. elegans daf-2(e1370) mutant fed on HB101 bacterial food source lived approximately 20% longer than OP50 control. |
So et al. |
2011 |
21354440 |
doi:10.1016/j.mad.2011.02.005 |
Lifespan Observations Database (ID: 4988) |
6 |
OB_004958 |
Caenorhabditis elegans |
clk-1(qm30) |
|
|
Other Ageing Factor Name |
Additional Information |
Food source |
Eggs were washed three times with Sbasal and transferred to plates containing a lawn of bacteria producing UQ10 or the standard bacteria strain OP50 (producing UQ8). |
|
increased |
18.75% |
19 |
16 |
days |
mean |
20 |
℃ |
|
Lifespan of clk-1 mutants are all significantly different from N2. Only clk-1 lifespan fed with UQ10 was significantly different (18%) from the clk-1 fed with UQ6, UQ7, UQ8, UQ9 and OP50. |
Yang et al. |
2009 |
19428456 |
doi:10.1016/j.mad.2009.03.003 |
Lifespan Observations Database (ID: 4644) |
7 |
OB_004963 |
Caenorhabditis elegans |
N2 |
|
|
Other Ageing Factor Name |
Additional Information |
Food source |
E. coli HB101 has leucine and proline auxotroph phenotype relative to E. coli OP50 has a uracil auxotroph phenotype control. |
|
increased |
10.62% |
17.7 |
16 |
days |
mean |
20 |
℃ |
|
C. elegans N2 fed on HB101 bacterial food source lived approximately 11% longer than OP50 control. |
So et al. |
2011 |
21354440 |
doi:10.1016/j.mad.2011.02.005 |
Lifespan Observations Database (ID: 4984) |
8 |
OB_004956 |
Caenorhabditis elegans |
clk-1(qm30) |
|
|
Other Ageing Factor Name |
Additional Information |
Food source |
Eggs were washed three times with Sbasal and transferred to plates containing a lawn of bacteria producing UQ8 or the standard bacteria strain OP50 (producing UQ8). |
|
increased |
6.25% |
17 |
16 |
days |
mean |
20 |
℃ |
|
The overall and adult lifespan of clk-1 fed with OP50 and UQ8 were similar, indicating the animals lifespan is not influenced by the different parental strain of bacteria. Lifespan of clk-1 mutants are all significantly different from N2. Only clk-1 lifespan fed with UQ10 was significantly different from the clk-1 fed with UQ6, UQ7, UQ8, UQ9 and OP50. Lifespan of clk-1(qm30) was not significantly different with UQ8 as food source relative to OP50. |
Yang et al. |
2009 |
19428456 |
doi:10.1016/j.mad.2009.03.003 |
Lifespan Observations Database (ID: 4642) |
9 |
OB_004957 |
Caenorhabditis elegans |
clk-1(qm30) |
|
|
Other Ageing Factor Name |
Additional Information |
Food source |
Eggs were washed three times with Sbasal and transferred to plates containing a lawn of bacteria producing UQ9 or the standard bacteria strain OP50 (producing UQ8). |
|
increased |
6.25% |
17 |
16 |
days |
mean |
20 |
℃ |
|
The overall and adult lifespan of clk-1 fed with OP50 and UQ8 were similar, indicating the animals lifespan is not influenced by the different parental strain of bacteria. Lifespan of clk-1 mutants are all significantly different from N2. Only clk-1 lifespan fed with UQ10 was significantly different from the clk-1 fed with UQ6, UQ7, UQ8, UQ9 and OP50. Lifespan of clk-1(qm30) was not significantly different with UQ9 as food source relative to OP50. |
Yang et al. |
2009 |
19428456 |
doi:10.1016/j.mad.2009.03.003 |
Lifespan Observations Database (ID: 4643) |
10 |
OB_004955 |
Caenorhabditis elegans |
clk-1(qm30) |
|
|
Other Ageing Factor Name |
Additional Information |
Food source |
Eggs were washed three times with Sbasal and transferred to plates containing a lawn of bacteria producing UQ7 or the standard bacteria strain OP50 (producing UQ8). |
|
none |
0.00% |
16 |
16 |
days |
mean |
20 |
℃ |
|
The overall and adult lifespan of clk-1 fed with OP50 and UQ8 were similar, indicating the animals lifespan is not influenced by the different parental strain of bacteria. Lifespan of clk-1 mutants are all significantly different from N2. Only clk-1 lifespan fed with UQ10 was significantly different from the clk-1 fed with UQ6, UQ7, UQ8, UQ9 and OP50. Lifespan of clk-1(qm30) was not significantly different with UQ7 as food source relative to OP50. |
Yang et al. |
2009 |
19428456 |
doi:10.1016/j.mad.2009.03.003 |
Lifespan Observations Database (ID: 4641) |
11 |
OB_004954 |
Caenorhabditis elegans |
clk-1(qm30) |
|
|
Other Ageing Factor Name |
Additional Information |
Food source |
Eggs were washed three times with Sbasal and transferred to plates containing a lawn of bacteria producing either UQ6, UQ7, UQ8, UQ9 or UQ10, or the standard bacteria strain OP50 (producing UQ8). |
|
decreased |
-6.25% |
15 |
16 |
days |
mean |
20 |
℃ |
|
The overall and adult lifespan of clk-1 fed with OP50 and UQ8 were similar, indicating the animals lifespan is not influenced by the different parental strain of bacteria. Lifespan of clk-1 mutants are all significantly different from N2. Only clk-1 lifespan fed with UQ10 was significantly different from the clk-1 fed with UQ6, UQ7, UQ8, UQ9 and OP50. Lifespan of clk-1(qm30) was not significantly different with UQ6 as food source relative to OP50. |
Yang et al. |
2009 |
19428456 |
doi:10.1016/j.mad.2009.03.003 |
Lifespan Observations Database (ID: 4640) |
12 |
OB_005002 |
Caenorhabditis elegans |
N2 |
|
|
Other Ageing Factor Name |
Additional Information |
Food source |
Lactobacillus rhamnosus CNCM I-4317 |
|
decreased |
-13.33% |
13 |
15 |
days |
|
20 |
℃ |
|
Altogether, these results show that, among the 78 LAB strains analyzed; only Lactobacillus rhamnosus CNCM I-3690 strain induced a strong resistance to oxidative stress in C. elegans. CNCM I-4317 did not provide a significant increase in lifespan. |
Grompone et al. |
2012 |
23300685 |
doi:10.1371/journal.pone.0052493 |
Lifespan Observations Database (ID: 5267) |
13 |
OB_003199 |
Caenorhabditis elegans |
N2 |
Gene Symbol |
Species |
NCBI Gene ID |
Allele Type |
Allele Name |
Reference Allele Type |
Allele Change |
coq-8 |
Caenorhabditis elegans |
175647 |
deletion / null |
- |
unknown |
unknown |
|
|
Other Ageing Factor Name |
Additional Information |
Food source |
Animals fedd GD1 bacteria, Q-less E.coli. |
|
decreased |
-54.12% |
8.9 |
19.4 |
days |
mean |
|
|
|
N2 animals fed on Q-less E. coli GD1 bacteria showed extended average life span whereas coq-8 knockouts fed on the Q-less bacteria strain showed reduced average life span. |
Asencio et al. |
2009 |
19007804 |
doi:10.1016/j.mad.2008.10.004 |
Lifespan Observations Database (ID: 4610) |