1 |
OB_003431 |
Caenorhabditis elegans |
N2 |
Gene Symbol |
Species |
NCBI Gene ID |
Allele Type |
Allele Name |
Reference Allele Type |
Allele Change |
cdc-25.1 |
Caenorhabditis elegans |
172353 |
RNAi knockdown |
- |
unknown |
unknown |
sgk-1 |
Caenorhabditis elegans |
181697 |
loss of function |
ok538 |
unknown |
unknown |
|
|
Other Ageing Factor Name |
Additional Information |
UV-killed diet |
OP50-1 was grown in LB with 100 mg mL1 streptomycin, concentrated 20, and 80 L was spread onto NG plates. Plates were placed at ~23 C for 16 h then exposed to UV in a Stratagene Stratalinker 2400 for 4 min. |
|
increased |
132.67% |
606.8 |
260.8 |
|
mean |
25 |
℃ |
|
Lifespan of sgk-1(ok538) mutant on UV-killed OP50 was approximately 132% longer than N2 control on cdc-25.1 RNAi background. |
Evans et al. |
2008 |
18782349 |
doi:10.1111/j.1474-9726.2008.00435.x |
Lifespan Observations Database (ID: 4855) |
2 |
OB_003432 |
Caenorhabditis elegans |
N2 |
Gene Symbol |
Species |
NCBI Gene ID |
Allele Type |
Allele Name |
Reference Allele Type |
Allele Change |
cdc-25.1 |
Caenorhabditis elegans |
172353 |
RNAi knockdown |
- |
unknown |
unknown |
daf-2 |
Caenorhabditis elegans |
175410 |
loss of function |
e1370 |
unknown |
unknown |
|
|
Other Ageing Factor Name |
Additional Information |
UV-killed diet |
OP50-1 was grown in LB with 100 mg mL1 streptomycin, concentrated 20, and 80 L was spread onto NG plates. Plates were placed at ~23 C for 16 h then exposed to UV in a Stratagene Stratalinker 2400 for 4 min. |
|
increased |
50.30% |
377.4 |
251.1 |
|
mean |
25 |
℃ |
|
Lifespan of daf-2(e1370) mutant on UV-killed OP50 was approximately 50% longer than N2 control on cdc-25.1 RNAi background. |
Evans et al. |
2008 |
18782349 |
doi:10.1111/j.1474-9726.2008.00435.x |
Lifespan Observations Database (ID: 4856) |
3 |
OB_003433 |
Caenorhabditis elegans |
N2 |
Gene Symbol |
Species |
NCBI Gene ID |
Allele Type |
Allele Name |
Reference Allele Type |
Allele Change |
age-1 |
Caenorhabditis elegans |
174762 |
loss of function |
hx546 |
unknown |
unknown |
cdc-25.1 |
Caenorhabditis elegans |
172353 |
RNAi knockdown |
- |
unknown |
unknown |
|
|
Other Ageing Factor Name |
Additional Information |
UV-killed diet |
OP50-1 was grown in LB with 100 mg mL1 streptomycin, concentrated 20, and 80 L was spread onto NG plates. Plates were placed at ~23 C for 16 h then exposed to UV in a Stratagene Stratalinker 2400 for 4 min. |
|
increased |
39.31% |
349.8 |
251.1 |
|
mean |
25 |
℃ |
|
Lifespan of age-1(hx546) mutant on UV-killed OP50 was approximately 40% longer than N2 control on cdc-25.1 RNAi background. |
Evans et al. |
2008 |
18782349 |
doi:10.1111/j.1474-9726.2008.00435.x |
Lifespan Observations Database (ID: 4857) |
4 |
OB_003434 |
Caenorhabditis elegans |
N2 |
Gene Symbol |
Species |
NCBI Gene ID |
Allele Type |
Allele Name |
Reference Allele Type |
Allele Change |
cdc-25.1 |
Caenorhabditis elegans |
172353 |
RNAi knockdown |
- |
unknown |
unknown |
pdk-1 |
Caenorhabditis elegans |
180475 |
loss of function |
sa680 |
unknown |
unknown |
|
|
Other Ageing Factor Name |
Additional Information |
UV-killed diet |
OP50-1 was grown in LB with 100 mg mL1 streptomycin, concentrated 20, and 80 L was spread onto NG plates. Plates were placed at ~23 C for 16 h then exposed to UV in a Stratagene Stratalinker 2400 for 4 min. |
|
increased |
26.64% |
318 |
251.1 |
|
mean |
25 |
℃ |
|
Lifespan of pdk-1(sa680) mutant on UV-killed OP50 was approximately 27% longer than N2 control on cdc-25.1 RNAi background. |
Evans et al. |
2008 |
18782349 |
doi:10.1111/j.1474-9726.2008.00435.x |
Lifespan Observations Database (ID: 4858) |
5 |
OB_003430 |
Caenorhabditis elegans |
N2 |
Gene Symbol |
Species |
NCBI Gene ID |
Allele Type |
Allele Name |
Reference Allele Type |
Allele Change |
akt-2 |
Caenorhabditis elegans |
181524 |
loss of function |
ok393 |
unknown |
unknown |
cdc-25.1 |
Caenorhabditis elegans |
172353 |
RNAi knockdown |
- |
unknown |
unknown |
|
|
Other Ageing Factor Name |
Additional Information |
UV-killed diet |
OP50-1 was grown in LB with 100 mg mL1 streptomycin, concentrated 20, and 80 L was spread onto NG plates. Plates were placed at ~23 C for 16 h then exposed to UV in a Stratagene Stratalinker 2400 for 4 min. |
|
increased |
18.06% |
600.7 |
508.8 |
|
mean |
25 |
℃ |
|
Lifespan of akt-2(ok393) mutant on UV-killed food source was approximately 18% longer than N2 control on cdc-25.1 RNAi background. |
Evans et al. |
2008 |
18782349 |
doi:10.1111/j.1474-9726.2008.00435.x |
Lifespan Observations Database (ID: 4854) |
6 |
OB_003429 |
Caenorhabditis elegans |
N2 |
Gene Symbol |
Species |
NCBI Gene ID |
Allele Type |
Allele Name |
Reference Allele Type |
Allele Change |
akt-1 |
Caenorhabditis elegans |
179424 |
loss of function |
ok525 |
unknown |
unknown |
cdc-25.1 |
Caenorhabditis elegans |
172353 |
RNAi knockdown |
- |
unknown |
unknown |
|
|
Other Ageing Factor Name |
Additional Information |
UV-killed diet |
OP50-1 was grown in LB with 100 mg mL1 streptomycin, concentrated 20, and 80 L was spread onto NG plates. Plates were placed at ~23 C for 16 h then exposed to UV in a Stratagene Stratalinker 2400 for 4 min. |
|
increased |
14.62% |
583.2 |
508.8 |
|
mean |
25 |
℃ |
|
Lifespan of akt-1(ok525) mutant on UV-killed food source was approximately 15% longer than N2 control on cdc-25.1 RNAi background. |
Evans et al. |
2008 |
18782349 |
doi:10.1111/j.1474-9726.2008.00435.x |
Lifespan Observations Database (ID: 4853) |
7 |
OB_004551 |
Caenorhabditis elegans |
TJ1060 (spe-9(hc88); fer-15(b26)) |
|
Compound Name |
Quantity |
Quantity Unit |
Diallyl trisulfide (DATS) |
0 |
- |
|
Other Ageing Factor Name |
Additional Information |
UV-killed diet |
OP50-1 were UV irradiated prior to worm exposure. |
|
increased |
8.92% |
35.4 |
32.5 |
days |
mean |
20 |
℃ |
|
Mean lifespan of TJ1060 (spe-9(hc88); fer-15(b26)) double mutant worms treated with 5 M DATS on UV-killed OP50-1 was approximately 9% longer than TJ1060 (spe-9(hc88); fer-15(b26)) control lifespan. |
Powolny et al. |
2011 |
21296648 |
doi:10.1016/j.exger.2011.01.005 |
Lifespan Observations Database (ID: 5070) |
8 |
OB_004552 |
Caenorhabditis elegans |
TJ1060 (spe-9(hc88); fer-15(b26)) |
|
Compound Name |
Quantity |
Quantity Unit |
Diallyl trisulfide (DATS) |
0 |
- |
|
Other Ageing Factor Name |
Additional Information |
UV-killed diet |
OP50-1 were UV irradiated prior to worm exposure. |
|
increased |
6.46% |
34.6 |
32.5 |
days |
mean |
20 |
℃ |
|
Mean lifespan of TJ1060 (spe-9(hc88); fer-15(b26)) double mutant worms treated with 10 M DATS on UV-killed OP50-1 was approximately 6% longer than TJ1060 (spe-9(hc88); fer-15(b26)) control lifespan. |
Powolny et al. |
2011 |
21296648 |
doi:10.1016/j.exger.2011.01.005 |
Lifespan Observations Database (ID: 5071) |
9 |
OB_004550 |
Caenorhabditis elegans |
TJ1060 (spe-9(hc88); fer-15(b26)) |
|
Compound Name |
Quantity |
Quantity Unit |
Diallyl trisulfide (DATS) |
0 |
- |
|
Other Ageing Factor Name |
Additional Information |
UV-killed diet |
OP50-1 were UV irradiated prior to worm exposure. |
|
increased |
6.15% |
34.5 |
32.5 |
days |
mean |
20 |
℃ |
|
Mean lifespan of TJ1060 (spe-9(hc88); fer-15(b26)) double mutant worms treated with 2.5 M DATS on UV-killed OP50-1 was approximately 6% longer than TJ1060 (spe-9(hc88); fer-15(b26)) control lifespan. |
Powolny et al. |
2011 |
21296648 |
doi:10.1016/j.exger.2011.01.005 |
Lifespan Observations Database (ID: 5069) |