1 |
OB_005006 |
Caenorhabditis elegans |
N2 |
|
|
Other Ageing Factor Name |
Additional Information |
Diet |
Control N2 fed on Comamonas DA1877, while experimental were fed on Comamonas DA1877 diluted in E. coli OP50. |
|
increased |
29.41% |
22 |
17 |
days |
mean |
20 |
℃ |
|
Mean lifespan of N2 fed on Comamonas DA1877 diluted 1/200 in E.coli OP50 diet was approximately 29% greater than control Comamonas DA1877 alone. |
MacNeil et al. |
2013 |
23540701 |
doi:10.1016/j.cell.2013.02.049 |
Lifespan Observations Database (ID: 5372) |
2 |
OB_005007 |
Caenorhabditis elegans |
|
|
|
Other Ageing Factor Name |
Additional Information |
Diet |
Control N2 fed on Comamonas DA1877, while experimental were fed on Comamonas DA1877 diluted in E. coli OP50. |
|
increased |
11.76% |
19 |
17 |
days |
mean |
20 |
℃ |
|
Mean lifespan of N2 fed on Comamonas DA1877 diluted 1/1000 in E.coli OP50 diet was approximately 12% greater than control Comamonas DA1877 diet alone. |
MacNeil et al. |
2013 |
23540701 |
doi:10.1016/j.cell.2013.02.049 |
Lifespan Observations Database (ID: 5373) |
3 |
OB_004703 |
Caenorhabditis elegans |
N2 |
|
Compound Name |
Quantity |
Quantity Unit |
Metformin |
50 |
mM |
|
Other Ageing Factor Name |
Additional Information |
Diet |
Cultured on Bacillus subtilis. |
|
increased |
9.44% |
29.32 |
26.79 |
days |
mean |
20 |
℃ |
|
Metformin (50 mM) increased lifespan of worms cultured on B. subtilis by 9%. |
Cabreiro et al. |
2013 |
23540700 |
doi:10.1016/j.cell.2013.02.035 |
Lifespan Observations Database (ID: 5387) |
4 |
OB_004699 |
Caenorhabditis elegans |
N2 |
|
Compound Name |
Quantity |
Quantity Unit |
Metformin |
2 |
mM |
|
Other Ageing Factor Name |
Additional Information |
Diet |
N2 cultured on axenic plates. |
|
none |
-2.14% |
17.8 |
18.19 |
days |
mean |
20 |
℃ |
|
Lifespan of N2 cultured on axenic medium caused an increase in worm lifespan, typical of DR. Under these conditions, metformin did not in- crease worm lifespan, but instead markedly reduced it. |
Cabreiro et al. |
2013 |
23540700 |
doi:10.1016/j.cell.2013.02.035 |
Lifespan Observations Database (ID: 5383) |
5 |
OB_004700 |
Caenorhabditis elegans |
N2 |
|
Compound Name |
Quantity |
Quantity Unit |
Metformin |
10 |
mM |
|
Other Ageing Factor Name |
Additional Information |
Diet |
N2 cultured on axenic plates. |
|
decreased |
-6.27% |
17.05 |
18.19 |
days |
mean |
20 |
℃ |
|
Lifespan of N2 cultured on axenic medium caused an increase in worm lifespan, typical of DR. Under these conditions, metformin did not increase worm lifespan, but instead markedly reduced it. 10 mM metformin decreased lifespan by 6%. |
Cabreiro et al. |
2013 |
23540700 |
doi:10.1016/j.cell.2013.02.035 |
Lifespan Observations Database (ID: 5384) |
6 |
OB_005004 |
Caenorhabditis elegans |
|
|
|
Other Ageing Factor Name |
Additional Information |
Diet |
Control N2 fed on E. coli OP50, while experimental were fed on E. coli HT115. |
|
decreased |
-9.52% |
19 |
21 |
days |
mean |
20 |
℃ |
|
Mean lifespan of N2 fed on E. coli HT115 diet was approximately 10% shorter than control. |
MacNeil et al. |
2013 |
23540701 |
doi:10.1016/j.cell.2013.02.049 |
Lifespan Observations Database (ID: 5370) |
7 |
OB_005003 |
Caenorhabditis elegans |
|
|
|
Other Ageing Factor Name |
Additional Information |
Diet |
Control N2 fed on E. coli OP50, while experimental were fed on Comamonas DA1877. |
|
decreased |
-28.57% |
15 |
21 |
days |
mean |
20 |
℃ |
|
Mean lifespan of N2 fed on Comamonas DA1877 diet was approximately 28% shorter than control. |
MacNeil et al. |
2013 |
23540701 |
doi:10.1016/j.cell.2013.02.049 |
Lifespan Observations Database (ID: 5369) |
8 |
OB_005005 |
Caenorhabditis elegans |
|
|
|
Other Ageing Factor Name |
Additional Information |
Diet |
Control N2 fed on killed E. coli OP50, while experimental were fed on Comamonas DA1877. |
|
decreased |
-41.94% |
18 |
31 |
days |
mean |
20 |
℃ |
|
Mean lifespan of N2 fed on killed Comamonas DA1877 diet was approximately 42% shorter than control. |
MacNeil et al. |
2013 |
23540701 |
doi:10.1016/j.cell.2013.02.049 |
Lifespan Observations Database (ID: 5371) |