Gene: KSS1 - Saccharomyces cerevisiae
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Gene Symbol | : | KSS1 | ||||||||||||||||
NCBI Gene ID | : | 852931 | ||||||||||||||||
Species | : | Saccharomyces cerevisiae | ||||||||||||||||
Gene Synonyms | : | |||||||||||||||||
Gene Homologs | : | AgaP_AGAP009207 (Anopheles gambiae) | AGOS_ACL191C (Eremothecium gossypii) | KLLA0A02497g (Kluyveromyces lactis) | KSS1 (Saccharomyces cerevisiae) | MAPK1 (Bos taurus) | MAPK1 (Canis lupus familiaris) | mapk1 (Danio rerio) | MAPK1 (Gallus gallus) | MAPK1 (Homo sapiens) | MAPK1 (Macaca mulatta) | Mapk1 (Mus musculus) | MAPK1 (Pan troglodytes) | Mapk1 (Rattus norvegicus) | mpk-1 (Caenorhabditis elegans) | MPK6 (Arabidopsis thaliana) | Os06g0154500 (Oryza sativa) | rl (Drosophila melanogaster) | ||||||||||||||||
Ageing Relevance Analysis | : |
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Ageing Factor Stable ID | : | AF_009232 | ||||||||||||||||
Download | : | XML |
Protein Information
no protein information available
Observations
Ageing Phenotype
Data Type 1
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
# | Observation Stable ID | Species | Gene | Other Ageing Factor | Description | PubMed | Source | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
1 | OB_005480 | Saccharomyces cerevisiae |
|
Deletion resulted in increased sensitivity to heat shock and oxidative stress and a 33% reduction in median lifespan. | 17662940 | GenAge |
Data Type 2
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Organism | Ageing Factor | Lifespan Observation | Reference | ||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
# | Observation Stable ID | Species | Strain | Gene | Compound | Other Ageing Factor | Significant Lifespan Effect | Change | Observed Lifespan | Reference Lifespan | Lifespan Unit | Measure | Temperature | Temperature Unit | Sex/Mating Type | Description | Author | Year | PubMed | DOI | Source | ||||||||||||||
1 | OB_005481 | Saccharomyces cerevisiae |
|
decreased | -33.00% | Median | Deletion resulted in increased sensitivity to heat shock and oxidative stress and a 33% reduction in median lifespan. | Yan et al. | 2007 | 17662940 | doi:10.1016/j.cell.2007.05.038 | GenAge |
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:
- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
# | Observation Stable ID | Homology Group Genes | #EGHG | Description | Source | Homology Source |
---|---|---|---|---|---|---|
1 | OB_008839 | 2 | The HomoloGene homology group 37670 contains 2 genes with experimental evidence for ageing relevance (KSS1 - Saccharomyces cerevisiae | mpk-1 - Caenorhabditis elegans) and 15 other genes. | AgeFactDB Homology Analysis | HomoloGene homology group 37670 |
Sequences
no sequence information available
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Yan L, Vatner DE, O'Connor JP, Ivessa A, Ge H, Chen W, Hirotani S, Ishikawa Y, Sadoshima J, Vatner SF:
Type 5 adenylyl cyclase disruption increases longevity and protects against stress.
Cell. 2007; 130: 247-58.
PubMed (ID: 17662940), doi:10.1016/j.cell.2007.05.038
MeSH Terms: Adenylate Cyclase/metabolism; Isoenzymes/metabolism; Longevity/physiology; Oxidative Stress
Sources
Ageing-related Data Sources
- AgeFactDB Homology Analysis
- GenAge
Additional Data Sources
- AgeFactDB Pipeline
- HomoloGene
- NCBI Taxonomy
- PubMed