Gene: IKI3 - Saccharomyces cerevisiae(see also ageing factor AF_008811 *)
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Gene Symbol | : | IKI3 | ||||||||||||||||
NCBI Gene ID | : | 851100 * | ||||||||||||||||
Species | : | Saccharomyces cerevisiae | ||||||||||||||||
Gene Synonyms | : | |||||||||||||||||
Gene Homologs | : | AgaP_AGAP003979 (Anopheles gambiae) | AGOS_AER047C (Eremothecium gossypii) | Elp1 (Drosophila melanogaster) | IKBKAP (Canis lupus familiaris) | ikbkap (Danio rerio) | IKBKAP (Gallus gallus) | IKBKAP (Homo sapiens) | Ikbkap (Mus musculus) | IKBKAP (Pan troglodytes) | Ikbkap (Rattus norvegicus) | IKI3 (Saccharomyces cerevisiae) | iki3 (Schizosaccharomyces pombe) | KLLA0E05237g (Kluyveromyces lactis) | LOC505465 (Bos taurus) | LOC713524 (Macaca mulatta) | MGG_07174 (Magnaporthe oryzae) | NCU01486 (Neurospora crassa) | ||||||||||||||||
Ageing Relevance Analysis | : |
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Ageing Factor Stable ID | : | AF_009418 | ||||||||||||||||
Download | : | XML |
*
AgeFactDB contains further genes associated with gene symbol IKI3 and the species Saccharomyces cerevisiae: AF_008811
Protein Information
no protein information available
Observations
Ageing Phenotype
Data Type 1
no ageing phenotype observation—data type 1 available
Data Type 2
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Organism | Ageing Factor | Lifespan Observation | Reference | ||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
# | Observation Stable ID | Species | Strain | Gene | Compound | Other Ageing Factor | Significant Lifespan Effect | Change | Observed Lifespan | Reference Lifespan | Lifespan Unit | Measure | Temperature | Temperature Unit | Sex/Mating Type | Description | Author | Year | PubMed | DOI | Source | ||||||||||||||
1 | OB_007346 | Saccharomyces cerevisiae |
|
increased | unknown | Survival increased during early chronological aging (day 5-15); | Eisenberg et al. | 2009 | 19801973 | doi:10.1038/ncb1975 | GenAge |
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:
- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
# | Observation Stable ID | Homology Group Genes | #EGHG | Description | Source | Homology Source |
---|---|---|---|---|---|---|
1 | OB_008202 | 1 | The HomoloGene homology group 2699 contains 1 gene with experimental evidence for ageing relevance (IKI3 - Saccharomyces cerevisiae) and 16 other genes. | AgeFactDB Homology Analysis | HomoloGene homology group 2699 |
Sequences
no sequence information available
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Eisenberg T, Knauer H, Schauer A, Büttner S, Ruckenstuhl C, Carmona-Gutierrez D, Ring J, Schroeder S, Magnes C, Antonacci L, Fussi H, Deszcz L, Hartl R, Schraml E, Criollo A, Megalou E, Weiskopf D, Laun P, Heeren G, Breitenbach M, Grubeck-Loebenstein B, Herker E, Fahrenkrog B, Fröhlich KU, Sinner F, Tavernarakis N, Minois N, Kroemer G, Madeo F:
Induction of autophagy by spermidine promotes longevity.
Nat Cell Biol. 2009; 11: 1305-14.
PubMed (ID: 19801973), doi:10.1038/ncb1975
MeSH Terms: Autophagy/drug effects; Longevity/drug effects; Spermidine/pharmacology
Sources
Ageing-related Data Sources
- AgeFactDB Homology Analysis
- GenAge
- Lifespan Observations Database
Additional Data Sources
- AgeFactDB Pipeline
- HomoloGene
- NCBI Taxonomy
- PubMed