Gene: CG7834 - Drosophila melanogaster(see also ageing factor AF_009462 *)
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Gene Symbol | : | CG7834 | ||||||||||||||||
NCBI Gene ID | : | 43515 * | ||||||||||||||||
Species | : | Drosophila melanogaster | ||||||||||||||||
Gene Synonyms | : | |||||||||||||||||
Gene Homologs | : | AgaP_AGAP004653 (Anopheles gambiae) | AGOS_ACL129W (Eremothecium gossypii) | CELE_F23C8.5 (Caenorhabditis elegans) | CG7834 (Drosophila melanogaster) | CIR1 (Saccharomyces cerevisiae) | ETFB (Arabidopsis thaliana) | ETFB (Bos taurus) | ETFB (Canis lupus familiaris) | etfb (Danio rerio) | ETFB (Homo sapiens) | ETFB (Macaca mulatta) | Etfb (Mus musculus) | Etfb (Rattus norvegicus) | KLLA0E16391g (Kluyveromyces lactis) | MGG_01744 (Magnaporthe oryzae) | NCU07733 (Neurospora crassa) | Os04g0182800 (Oryza sativa) | SPAC1805.02c (Schizosaccharomyces pombe) | ||||||||||||||||
Ageing Relevance Analysis | : |
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Ageing Factor Stable ID | : | AF_009463 | ||||||||||||||||
Download | : | XML |
*
AgeFactDB contains further genes associated with gene symbol CG7834 and the species Drosophila melanogaster: AF_009462
Protein Information
Protein Name | Species | UniProt Accession Number | UniProt Entry Name | Protein Function | Sequence |
---|---|---|---|---|---|
CG7834, isoform A | Drosophila melanogaster | Q0KHZ6 (UniProtKB/TrEMBL) | Q0KHZ6_DROME (UniProtKB/TrEMBL) | View |
Observations
Ageing Phenotype
Data Type 1
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
# | Observation Stable ID | Species | Gene | Other Ageing Factor | Description | PubMed | Source | ||||||
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1 | OB_007940 | Drosophila melanogaster |
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Muscle specific RNAi knockdown of CG7834 which reduces its mRNA levels by 25-35%, significantly reduces the DR-dependent lifespan extension. CG7834 RNAi animals exhibit only a 14% increase compared to the 55% lifespan-increase in controls upon DR [Katewa et al. 2012]. | GenDR |
Data Type 2
no ageing phenotype observation—data type 2 available
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:
- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
# | Observation Stable ID | Homology Group Genes | #EGHG | Description | Source | Homology Source |
---|---|---|---|---|---|---|
1 | OB_009351 | 1 | The HomoloGene homology group 1503 contains 1 gene with experimental evidence for ageing relevance (CG7834 - Drosophila melanogaster) and 17 other genes. | AgeFactDB Homology Analysis | HomoloGene homology group 1503 |
Sequences
Q0KHZ6_DROME | Q0KHZ6 | CG7834, isoform A (Drosophila melanogaster) from UniProtKB/TrEMBL Length: 253 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 Q0KHZ6_DROME 1 MARVLVGVKRVIDYAVKVRVKPDKTGVVTQGVKHSMNPFDEIAVEEAVKLKEKKLAEEVIAVSVGPAQSQEVIRTALAMGADRGVHVEIPAAEYELLQPIHVSKILAKLALDEKADLVILGKQAIDDDANQTAQMTAAVLDWPQGTFCNKIEKTDAGLTITREIDGGLETIKTKTPAVLSADLRLNTPRYATLPNIMKAKKKPLKKVTAKDLGVDTSPRIEVISVEDPPVRQAGATVADVDALVAKLKEGGHI 253
References
no reference information available
Sources
Ageing-related Data Sources
- AgeFactDB Homology Analysis
- GenDR
Additional Data Sources
- AgeFactDB Pipeline
- HomoloGene
- NCBI Taxonomy
- UniProtKB/TrEMBL