Gene: GIPC3 - Homo sapiens
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Gene Symbol | : | GIPC3 | ||||||||||||
NCBI Gene ID | : | 126326 | ||||||||||||
Species | : | Homo sapiens | ||||||||||||
Gene Synonyms | : | |||||||||||||
Gene Homologs | : | AgaP_AGAP007674 (Anopheles gambiae) | GIPC3 (Bos taurus) | GIPC3 (Canis lupus familiaris) | GIPC3 (Homo sapiens) | GIPC3 (Macaca mulatta) | Gipc3 (Mus musculus) | GIPC3 (Pan troglodytes) | Gipc3 (Rattus norvegicus) | kermit (Drosophila melanogaster) | LOC100857667 (Gallus gallus) | zgc:136839 (Danio rerio) | ||||||||||||
Ageing Relevance Analysis | : |
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Ageing Factor Stable ID | : | AF_009497 | ||||||||||||
Download | : | XML |
Protein Information
Protein Name | Species | UniProt Accession Number | UniProt Entry Name | Protein Function | Sequence |
---|---|---|---|---|---|
PDZ domain-containing protein GIPC3 | Homo sapiens | Q8TF64 (UniProtKB/Swiss-Prot) | GIPC3_HUMAN (UniProtKB/Swiss-Prot) | Required for postnatal maturation of the hair bundle and long-term survival of hair cells and spiral ganglion. | View |
Observations
Ageing Phenotype
Data Type 1
no ageing phenotype observation—data type 1 available
Data Type 2
no ageing phenotype observation—data type 2 available
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:
- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
# | Observation Stable ID | Homology Group Genes | #EGHG | Description | Source | Homology Source |
---|---|---|---|---|---|---|
1 | OB_008162 | 1 | The HomoloGene homology group 77068 contains 1 gene with experimental evidence for ageing relevance (kermit - Drosophila melanogaster) and 10 other genes. | AgeFactDB Homology Analysis | HomoloGene homology group 77068 |
Sequences
GIPC3_HUMAN | Q8TF64 | PDZ domain-containing protein GIPC3 (Homo sapiens) from UniProtKB/Swiss-Prot Length: 312 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 GIPC3_HUMAN 1 MEGAAAREARGTETPRASAPPPAPSEPPAAPRARPRLVFRTQLAHGSPTGKIEGFTNVRELYAKIAEAFGIAPTEILFCTLNSHKVDMQKLLGGQIGLEDFIFAHVRGETKEVEVTKTEDALGLTITDNGAGYAFIKRIKEGSIINRIEAVCVGDSIEAINDHSIVGCRHYEVAKMLRELPKSQPFTLRLVQPKRAFDMIGQRSRSSKCPVEAKVTSGRETLRLRSGGAATVEEAPSEFEEEASRKVDDLLESYMGIRDPELASTMVETSKKTASAQEFARCLDSVLGEFAFPDEFVVEVWAAIGEAREACG 312
References
no reference information available
Sources
Ageing-related Data Sources
- AgeFactDB Homology Analysis
Additional Data Sources
- AgeFactDB Pipeline
- HomoloGene
- UniProtKB/Swiss-Prot