Gene: UCP3 - Canis lupus familiaris
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Gene Symbol | : | UCP3 | ||||||||||||
NCBI Gene ID | : | 403575 | ||||||||||||
Species | : | Canis lupus familiaris | ||||||||||||
Gene Synonyms | : | |||||||||||||
Gene Homologs | : | PUMP2 (Arabidopsis thaliana) | ucp1 (Danio rerio) | UCP3 (Bos taurus) | UCP3 (Canis lupus familiaris) | UCP3 (Gallus gallus) | UCP3 (Homo sapiens) | UCP3 (Macaca mulatta) | Ucp3 (Mus musculus) | UCP3 (Pan troglodytes) | Ucp3 (Rattus norvegicus) | ||||||||||||
Ageing Relevance Analysis | : |
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Ageing Factor Stable ID | : | AF_009923 | ||||||||||||
Download | : | XML |
Protein Information
Protein Name | Species | UniProt Accession Number | UniProt Entry Name | Protein Function | Sequence |
---|---|---|---|---|---|
Mitochondrial uncoupling protein 3 | Canis lupus familiaris | Q9N2I9 (UniProtKB/Swiss-Prot) | UCP3_CANFA (UniProtKB/Swiss-Prot) | UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation. As a result, energy is dissipated in the form of heat. May play a role in the modulation of tissue respiratory control. Participates in thermogenesis and energy balance. | View |
Observations
Ageing Phenotype
Data Type 1
no ageing phenotype observation—data type 1 available
Data Type 2
no ageing phenotype observation—data type 2 available
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:
- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
# | Observation Stable ID | Homology Group Genes | #EGHG | Description | Source | Homology Source | |||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | OB_008224 |
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1 | The HomoloGene homology group 2517 contains 1 gene with experimental evidence for ageing relevance (UCP3 - Homo sapiens) and 9 other genes. | AgeFactDB Homology Analysis | HomoloGene homology group 2517 |
Sequences
UCP3_CANFA | Q9N2I9 | Mitochondrial uncoupling protein 3 (Canis lupus familiaris) from UniProtKB/Swiss-Prot Length: 311 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 UCP3_CANFA 1 MVGLKPSEVPPTTAVKFLGAGTAACFADLLTFPLDTAKVRLQIQGENQATQAARRIQYRGVLGTILTMVRTEGPRSPYNGLVAGLQRQMSFASIRIGLYDSVKQFYTPKGSDHSSITTRILAGCTTGAMAVSCAQPTDVVKVRFQASIHLGAGSNRKYSGTMDAYRTIAREEGVRGLWKGTLPNITRNAIVNCAEMVTYDIIKEKLLDYHLLTDNFPCHLISAFGAGFCATVVASPVDVVKTRYMNSPPGQYCSPLDCMLKMVTQEGPTAFYKGFTPSFLRLGTWNVVMFVTYEQLKRALMKVQMLRESPF 311
References
no reference information available
Sources
Ageing-related Data Sources
- AgeFactDB Homology Analysis
Additional Data Sources
- AgeFactDB Pipeline
- HomoloGene
- UniProtKB/Swiss-Prot