Gene: Impa1 - Rattus norvegicus
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Gene Symbol | : | Impa1 | ||||||||||||
NCBI Gene ID | : | 83523 | ||||||||||||
Species | : | Rattus norvegicus | ||||||||||||
Gene Synonyms | : | |||||||||||||
Gene Homologs | : | AgaP_AGAP006570 (Anopheles gambiae) | CG9391 (Drosophila melanogaster) | IMPA1 (Bos taurus) | IMPA1 (Canis lupus familiaris) | impa1 (Danio rerio) | IMPA1 (Gallus gallus) | IMPA1 (Homo sapiens) | IMPA1 (Macaca mulatta) | Impa1 (Mus musculus) | Impa1 (Rattus norvegicus) | INM1 (Saccharomyces cerevisiae) | INM2 (Saccharomyces cerevisiae) | LOC100613673 (Pan troglodytes) | MGG_06165 (Magnaporthe oryzae) | NCU06348 (Neurospora crassa) | Os03g0587000 (Oryza sativa) | ttx-7 (Caenorhabditis elegans) | VTC4 (Arabidopsis thaliana) | ||||||||||||
Ageing Relevance Analysis | : |
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Ageing Factor Stable ID | : | AF_010224 | ||||||||||||
Download | : | XML |
Protein Information
Protein Name | Species | UniProt Accession Number | UniProt Entry Name | Protein Function | Sequence |
---|---|---|---|---|---|
Inositol monophosphatase 1 | Rattus norvegicus | P97697 (UniProtKB/Swiss-Prot) | IMPA1_RAT (UniProtKB/Swiss-Prot) | Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. Can use myo-inositol monophosphates, myo-inositol 1,3-diphosphate, myo-inositol 1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. | View |
Observations
Ageing Phenotype
Data Type 1
no ageing phenotype observation—data type 1 available
Data Type 2
no ageing phenotype observation—data type 2 available
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:
- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
# | Observation Stable ID | Homology Group Genes | #EGHG | Description | Source | Homology Source |
---|---|---|---|---|---|---|
1 | OB_008258 | 2 | The HomoloGene homology group 4043 contains 2 genes with experimental evidence for ageing relevance (INM1 - Saccharomyces cerevisiae | INM2 - Saccharomyces cerevisiae) and 16 other genes. | AgeFactDB Homology Analysis | HomoloGene homology group 4043 |
Sequences
IMPA1_RAT | P97697 | Inositol monophosphatase 1 (Rattus norvegicus) from UniProtKB/Swiss-Prot Length: 277 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 IMPA1_RAT 1 MADPWQECMDYAVILARQAGEMIREALKNKMDVMIKSSPADLVTVTDQKVEKMLMSSIKEKYPYHSFIGEESVASGEKTVFTEQPTWIIDPIDGTTNFVHRFPFVAVSIGFVVNKEMEFGVVYSCVEDKMYTGRKGKGAFCNGQKLRVSQQEDITKSLLVTELGSSRKPETLRIVLSNMERLCSIPIHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDMAGAGIIVIEAGGVLLDVTGGPFDLMSRRIIAASNIALAERIAKELEIIPLQRDDES 277
References
no reference information available
Sources
Ageing-related Data Sources
- AgeFactDB Homology Analysis
Additional Data Sources
- AgeFactDB Pipeline
- HomoloGene
- UniProtKB/Swiss-Prot