Gene: EIF2 BETA - Arabidopsis thaliana
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Gene Symbol | : | EIF2 BETA | ||||||||||||
NCBI Gene ID | : | 832216 | ||||||||||||
Species | : | Arabidopsis thaliana | ||||||||||||
Gene Synonyms | : | |||||||||||||
Gene Homologs | : | AgaP_AGAP007218 (Anopheles gambiae) | AGOS_AFL145W (Eremothecium gossypii) | eIF-2beta (Drosophila melanogaster) | EIF2 BETA (Arabidopsis thaliana) | EIF2S2 (Bos taurus) | EIF2S2 (Canis lupus familiaris) | eif2s2 (Danio rerio) | EIF2S2 (Gallus gallus) | EIF2S2 (Homo sapiens) | EIF2S2 (Macaca mulatta) | Eif2s2 (Mus musculus) | EIF2S2 (Pan troglodytes) | Eif2s2 (Rattus norvegicus) | iftb-1 (Caenorhabditis elegans) | KLLA0D08932g (Kluyveromyces lactis) | MGG_00789 (Magnaporthe oryzae) | NCU04640 (Neurospora crassa) | Os03g0333300 (Oryza sativa) | Os07g0681000 (Oryza sativa) | SUI3 (Saccharomyces cerevisiae) | tif212 (Schizosaccharomyces pombe) | ||||||||||||
Ageing Relevance Analysis | : |
|
||||||||||||
Ageing Factor Stable ID | : | AF_016474 | ||||||||||||
Download | : | XML |
Protein Information
Protein Name | Species | UniProt Accession Number | UniProt Entry Name | Protein Function | Sequence |
---|---|---|---|---|---|
Translation initiation factor eIF-2 beta subunit | Arabidopsis thaliana | F4K6W6 (UniProtKB/TrEMBL) | F4K6W6_ARATH (UniProtKB/TrEMBL) | View | |
Eukaryotic translation initiation factor 2 subunit beta | Arabidopsis thaliana | Q41969 (UniProtKB/Swiss-Prot) | IF2B_ARATH (UniProtKB/Swiss-Prot) | eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B. | View |
Observations
Ageing Phenotype
Data Type 1
no ageing phenotype observation—data type 1 available
Data Type 2
no ageing phenotype observation—data type 2 available
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:
- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
Sequences
F4K6W6_ARATH | F4K6W6 | Translation initiation factor eIF-2 beta subunit (Arabidopsis thaliana) from UniProtKB/TrEMBL Length: 267 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 F4K6W6_ARATH 1 MADEINEIREEQELAPFDPSKKKKKKKVVIQEPVEDLAESSQTEKSDSLPVNDGLESSFTGMKKKKKKPTESSLLNNESVDAGEDLDEIANDEQEGEEGIVLQQRYPWEGSERDYIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMQYLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYITDYVICLGCKSPDTILSKENRLFFLRCEKCGSQRSVAPIKTGFVARVSRRKT 267
IF2B_ARATH | Q41969 | Eukaryotic translation initiation factor 2 subunit beta (Arabidopsis thaliana) from UniProtKB/Swiss-Prot Length: 268 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 IF2B_ARATH 1 MADEINEIREEQEQLAPFDPSKKKKKKKVVIQEPVEDLAESSQTEKSDSLPVNDGLESSFTGMKKKKKKPTESSLLNNESVDAGEDLDEIANDEQEGEEGIVLQQRYPWEGSERDYIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTMHRQPDHVMQYLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYITDYVICLGCKSPDTILSKENRLFFLRCEKCGSQRSVAPIKTGFVARVSRRKT 268
References
no reference information available
Sources
Ageing-related Data Sources
- AgeFactDB Homology Analysis
Additional Data Sources
- AgeFactDB Pipeline
- HomoloGene
- UniProtKB/Swiss-Prot
- UniProtKB/TrEMBL