Gene: GTF2H2 - Bos taurus
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Gene Symbol | : | GTF2H2 | ||||||||||||
NCBI Gene ID | : | 511829 | ||||||||||||
Species | : | Bos taurus | ||||||||||||
Gene Synonyms | : | |||||||||||||
Gene Homologs | : | AgaP_AGAP010559 (Anopheles gambiae) | AGOS_ADR338C (Eremothecium gossypii) | AT1G05055.1 (Arabidopsis thaliana) | GTF2H2 (Bos taurus) | GTF2H2 (Canis lupus familiaris) | gtf2h2 (Danio rerio) | GTF2H2 (Homo sapiens) | GTF2H2 (Macaca mulatta) | Gtf2h2 (Mus musculus) | GTF2H2 (Pan troglodytes) | Gtf2h2 (Rattus norvegicus) | KLLA0E09615g (Kluyveromyces lactis) | LOC100858972 (Gallus gallus) | MGG_06690 (Magnaporthe oryzae) | NCU01831 (Neurospora crassa) | Os04g0508900 (Oryza sativa) | Ssl1 (Drosophila melanogaster) | SSL1 (Saccharomyces cerevisiae) | ssl1 (Schizosaccharomyces pombe) | T16H12.4 (Caenorhabditis elegans) | ||||||||||||
Ageing Relevance Analysis | : |
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Ageing Factor Stable ID | : | AF_019017 | ||||||||||||
Download | : | XML |
Protein Information
Protein Name | Species | UniProt Accession Number | UniProt Entry Name | Protein Function | Sequence |
---|---|---|---|---|---|
General transcription factor IIH subunit 2 | Bos taurus | Q2TBV5 (UniProtKB/Swiss-Prot) | TF2H2_BOVIN (UniProtKB/Swiss-Prot) | Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. The N-terminus interacts with and regulates XPD whereas an intact C-terminus is required for a successful escape of RNAP II form the promoter. | View |
Observations
Ageing Phenotype
Data Type 1
no ageing phenotype observation—data type 1 available
Data Type 2
no ageing phenotype observation—data type 2 available
Homology Analysis
Ageing Relevance:
- yes (Exp. Analysis)
- yes, but no ageing factor assigned (Exp. Analysis)
- no (Exp. Analysis)
- putative (Comp. Analysis)
Legend:
- #EGHG:
- Number of Experimentally Confirmed Ageing-related Genes In Homology Group
Sequences
TF2H2_BOVIN | Q2TBV5 | General transcription factor IIH subunit 2 (Bos taurus) from UniProtKB/Swiss-Prot Length: 395 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 TF2H2_BOVIN 1 MDEEPERTKRWEGGYERTWEILKEDESGSLKATIEDILFKAKRKRVFEHHGQVRLGMMRHLYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTELSGNPRKHITSLKKAVDMTCHGEPSLYNSLSMAMQTLKHMPGHTSREVLIIFSSLTTCDPSNIYDLIKSLKAAKIRVSIIGLSAEVRVCTALARETGGTYHVILDESHYKELLTHHVSPPPASSNSECSLIRMGFPQHTIASLSDQDAKPSFSMAHLDSNTEPGLTLGGYFCPQCRAKYCELPVECKICGLTLVSAPHLARSYHHLFPLDAFQEIPLEEHNGERFCYACQGELKDQHVYVCSVCQNVFCVDCDVFVHDSLHCCPGCIHKIPVPSGI 395
References
no reference information available
Sources
Ageing-related Data Sources
- AgeFactDB Homology Analysis
Additional Data Sources
- AgeFactDB Pipeline
- HomoloGene
- UniProtKB/Swiss-Prot