Ageing Phenotype Observation—Data Type 2 : OB_000041
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Species | : | Caenorhabditis elegans | ||||||||||||||||||||||||||||
Strain | : | N2 | ||||||||||||||||||||||||||||
Gene | : |
|
||||||||||||||||||||||||||||
Compound | : | |||||||||||||||||||||||||||||
Other Ageing Factor | : | |||||||||||||||||||||||||||||
Significant Lifespan Effect | : | increased | ||||||||||||||||||||||||||||
Change | : | 7.11% | ||||||||||||||||||||||||||||
Observed Lifespan | : | 22.6 | ||||||||||||||||||||||||||||
Reference Lifespan | : | 21.1 | ||||||||||||||||||||||||||||
Lifespan Unit | : | days | ||||||||||||||||||||||||||||
Measure | : | mean | ||||||||||||||||||||||||||||
Temperature | : | 20 | ||||||||||||||||||||||||||||
Temperature Unit | : | ℃ | ||||||||||||||||||||||||||||
Sex/Mating Type | : | hermaphrodite | ||||||||||||||||||||||||||||
Description | : | RNAi knock-down of both hif-1 and vhl-1 had no significant effect on life span in the RNAi sensitive rrf-3(pk1426) background. | ||||||||||||||||||||||||||||
Observation Stable ID | : | OB_000041 | ||||||||||||||||||||||||||||
Source | : | Lifespan Observations Database (ID: 1037) | ||||||||||||||||||||||||||||
Download | : | XML |
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Mehta R, Steinkraus KA, Sutphin GL, Ramos FJ, Shamieh LS, Huh A, Davis C, Chandler-Brown D, Kaeberlein M:
Proteasomal regulation of the hypoxic response modulates aging in C. elegans.
Science. 2009; 324: 1196-8.
PubMed (ID: 19372390), PubMed Central (ID: PMC2737476), doi:10.1126/science.1173507
MeSH Terms: Aging/physiology; Caenorhabditis elegans Proteins/metabolism; Caenorhabditis elegans/physiology; Cullin Proteins/metabolism; Oxygen/physiology; Proteasome Endopeptidase Complex/metabolism; Transcription Factors/metabolism