Ageing Phenotype Observation—Data Type 2 : OB_000045
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Species | : | Saccharomyces cerevisiae | ||||||||||||||
Strain | : | PSY316AT | ||||||||||||||
Gene | : |
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Compound | : | |||||||||||||||
Other Ageing Factor | : | |||||||||||||||
Significant Lifespan Effect | : | none | ||||||||||||||
Change | : | -2.58% | ||||||||||||||
Observed Lifespan | : | 22.7 | ||||||||||||||
Reference Lifespan | : | 23.3 | ||||||||||||||
Lifespan Unit | : | divisions | ||||||||||||||
Measure | : | mean | ||||||||||||||
Temperature | : | 30 | ||||||||||||||
Temperature Unit | : | ℃ | ||||||||||||||
Sex/Mating Type | : | matalpha | ||||||||||||||
Description | : | Integration of a second copy of SIR2 failed to significantly alter life span in the PSY316 strain background. This differs from the increased life span observed for SIR2-overexpression in wth W303 and BY4742 strain backgrounds. | ||||||||||||||
Source | : | Lifespan Observations Database (ID: 1040) | ||||||||||||||
Observation Stable ID | : | OB_000045 | ||||||||||||||
Download | : | XML |
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Kaeberlein M, McDonagh T, Heltweg B, Hixon J, Westman EA, Caldwell SD, Napper A, Curtis R, DiStefano PS, Fields S, Bedalov A, Kennedy BK:
Substrate-specific activation of sirtuins by resveratrol.
J Biol Chem. 2005; 280: 17038-45.
PubMed (ID: 15684413), doi:10.1074/jbc.M500655200
MeSH Terms: Antioxidants/pharmacology; Histone Deacetylases/chemistry; Sirtuins/antagonists & inhibitors; Sirtuins/chemistry; Stilbenes/pharmacology