Ageing Phenotype Observation—Data Type 2 : OB_000334
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Species | : | Saccharomyces cerevisiae | |||||||||||||||||||||
Strain | : | W303AR5 | |||||||||||||||||||||
Gene | : |
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Compound | : | ||||||||||||||||||||||
Other Ageing Factor | : | ||||||||||||||||||||||
Significant Lifespan Effect | : | none | |||||||||||||||||||||
Change | : | 0.00% | |||||||||||||||||||||
Observed Lifespan | : | 22 | |||||||||||||||||||||
Reference Lifespan | : | 22 | |||||||||||||||||||||
Lifespan Unit | : | divisions | |||||||||||||||||||||
Measure | : | mean | |||||||||||||||||||||
Temperature | : | 30 | |||||||||||||||||||||
Temperature Unit | : | ℃ | |||||||||||||||||||||
Sex/Mating Type | : | mata | |||||||||||||||||||||
Description | : | Mutation of Sir2 asparagine 345 to alanine modestly decreased activity but did not shorten life span. | |||||||||||||||||||||
Source | : | Lifespan Observations Database (ID: 160) | |||||||||||||||||||||
Observation Stable ID | : | OB_000334 | |||||||||||||||||||||
Download | : | XML |
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Imai S, Armstrong CM, Kaeberlein M, Guarente L:
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase.
Nature. 2000; 403: 795-800.
PubMed (ID: 10693811), doi:10.1038/35001622
MeSH Terms: Fungal Proteins/metabolism; Gene Silencing; Histone Deacetylases/metabolism; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Trans-Activators/metabolism