Ageing Phenotype Observation—Data Type 2 : OB_000522
Last modified: Dec 09, 2014. Release 1 • Page created: Jun 02, 2024
Summary
Species | : | Saccharomyces cerevisiae | ||||||||||||||
Strain | : | W303AR5 | ||||||||||||||
Gene | : |
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Compound | : | |||||||||||||||
Other Ageing Factor | : | |||||||||||||||
Significant Lifespan Effect | : | increased | ||||||||||||||
Change | : | 30.43% | ||||||||||||||
Observed Lifespan | : | 27 | ||||||||||||||
Reference Lifespan | : | 20.7 | ||||||||||||||
Lifespan Unit | : | |||||||||||||||
Measure | : | mean | ||||||||||||||
Temperature | : | 30 | ||||||||||||||
Temperature Unit | : | ℃ | ||||||||||||||
Sex/Mating Type | : | mata | ||||||||||||||
Description | : | Deletion of FOB1 increases life span and restores the short life span of a SIR2 deletion mutant back to wild type levels. | ||||||||||||||
Source | : | Lifespan Observations Database (ID: 1784) | ||||||||||||||
Observation Stable ID | : | OB_000522 | ||||||||||||||
Download | : | XML |
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Kaeberlein M, McVey M, Guarente L:
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms.
Genes Dev. 1999; 13: 2570-80.
PubMed (ID: 10521401), PubMed Central (ID: PMC317077)
MeSH Terms: DNA-Binding Proteins/physiology; Fungal Proteins/physiology; Histone Deacetylases; Saccharomyces cerevisiae Proteins; Saccharomyces cerevisiae/physiology; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Trans-Activators/physiology