Ageing Phenotype Observation—Data Type 2 : OB_000844
Last modified: Dec 09, 2014. Release 1 • Page created: Jun 02, 2024
Summary
Species | : | Caenorhabditis elegans | ||||||||||||||
Strain | : | N2 | ||||||||||||||
Gene | : |
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Compound | : | |||||||||||||||
Other Ageing Factor | : |
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Significant Lifespan Effect | : | decreased | ||||||||||||||
Change | : | -12.50% | ||||||||||||||
Observed Lifespan | : | 21 | ||||||||||||||
Reference Lifespan | : | 24 | ||||||||||||||
Lifespan Unit | : | days | ||||||||||||||
Measure | : | median | ||||||||||||||
Temperature | : | 20 | ||||||||||||||
Temperature Unit | : | ℃ | ||||||||||||||
Sex/Mating Type | : | hermaphrodite | ||||||||||||||
Description | : | Dietary restriction by bacterial deprivation increases the life span of wild type and daf-16 mutants, but fails to increase the life span of hsf-1 mutants. | ||||||||||||||
Observation Stable ID | : | OB_000844 | ||||||||||||||
Source | : | Lifespan Observations Database (ID: 2125) | ||||||||||||||
Download | : | XML |
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Steinkraus KA, Smith ED, Davis C, Carr D, Pendergrass WR, Sutphin GL, Kennedy BK, Kaeberlein M:
Dietary restriction suppresses proteotoxicity and enhances longevity by an hsf-1-dependent mechanism in Caenorhabditis elegans.
Aging Cell. 2008; 7: 394-404.
PubMed (ID: 18331616), PubMed Central (ID: PMC2709959), doi:10.1111/j.1474-9726.2008.00385.x
MeSH Terms: Caenorhabditis elegans Proteins/metabolism; Caenorhabditis elegans/metabolism; Caloric Restriction; Longevity/physiology; Transcription Factors/metabolism