Ageing Phenotype Observation—Data Type 2 : OB_000927
Last modified: Dec 09, 2014. Release 1 • Page created: Jun 02, 2024
Summary
Species |
: |
Caenorhabditis elegans |
Strain |
: |
N2 |
Gene |
: |
Gene Symbol |
Species |
NCBI Gene ID |
Allele Type |
Allele Name |
Reference Allele Type |
Allele Change |
daf-9 |
Caenorhabditis elegans |
180889 |
loss of function |
dh6;dhEx24 |
unknown |
unknown |
|
Compound |
: |
|
Other Ageing Factor |
: |
Other Ageing Factor Name |
Additional Information |
Germ cell ablation |
Z2, Z3 laser ablation at L1 larval stage |
Somatic gonad ablation |
Z1, Z4 laser ablation at L1 larval stage |
|
Significant Lifespan Effect |
: |
increased |
Change |
: |
8.12% |
Observed Lifespan |
: |
21.3 |
Reference Lifespan |
: |
19.7 |
Lifespan Unit |
: |
days |
Measure |
: |
mean |
Temperature |
: |
20 |
Temperature Unit |
: |
℃ |
Sex/Mating Type |
: |
hermaphrodite |
Description |
: |
Additional removal of the somatic gonadal precursors, Z1 and Z4, from germline-deficient animals abrogates the extension generated by Z2 and Z3 ablation, suggesting that opposing signals from germline and somatic gonad could regulate longevity. |
Observation Stable ID |
: |
OB_000927 |
Source |
: |
Lifespan Observations Database (ID: 2235) |
Download |
: |
XML |
References
MeSH Terms:
Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms.
They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page.
MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Gerisch B, Weitzel C, Kober-Eisermann C, Rottiers V, Antebi A:
A hormonal signaling pathway influencing C. elegans metabolism, reproductive development, and life span.
Dev Cell. 2001; 1: 841-51.
PubMed (ID: 11740945)
MeSH Terms: Caenorhabditis elegans Proteins/metabolism; Caenorhabditis elegans/physiology; Larva/physiology; Receptors, Cytoplasmic and Nuclear/metabolism; Signal Transduction
Sources
Ageing-related Data Sources
Additional Data Sources