Ageing Phenotype Observation—Data Type 2 : OB_001232
Last modified: Dec 09, 2014. Release 1 • Page created: May 19, 2024
Summary
Species |
: |
Saccharomyces cerevisiae |
Strain |
: |
BY4741 |
Gene |
: |
Gene Symbol |
Species |
NCBI Gene ID |
Allele Type |
Allele Name |
Reference Allele Type |
Allele Change |
spe1 |
Saccharomyces cerevisiae |
|
deletion / null |
- |
unknown |
unknown |
|
Compound |
: |
Compound Name |
Quantity |
Quantity Unit |
Spermidine |
0.1 |
mM |
|
Other Ageing Factor |
: |
|
Significant Lifespan Effect |
: |
none |
Change |
: |
0.00% |
Observed Lifespan |
: |
10 |
Reference Lifespan |
: |
10 |
Lifespan Unit |
: |
days |
Measure |
: |
median |
Temperature |
: |
30 |
Temperature Unit |
: |
℃ |
Sex/Mating Type |
: |
mata |
Description |
: |
Polyamine depletion shortens chronological life span. |
Observation Stable ID |
: |
OB_001232 |
Source |
: |
Lifespan Observations Database (ID: 2560) |
Download |
: |
XML |
References
MeSH Terms:
Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms.
They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page.
MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Eisenberg T, Knauer H, Schauer A, Büttner S, Ruckenstuhl C, Carmona-Gutierrez D, Ring J, Schroeder S, Magnes C, Antonacci L, Fussi H, Deszcz L, Hartl R, Schraml E, Criollo A, Megalou E, Weiskopf D, Laun P, Heeren G, Breitenbach M, Grubeck-Loebenstein B, Herker E, Fahrenkrog B, Fröhlich KU, Sinner F, Tavernarakis N, Minois N, Kroemer G, Madeo F:
Induction of autophagy by spermidine promotes longevity.
Nat Cell Biol. 2009; 11: 1305-14.
PubMed (ID: 19801973), doi:10.1038/ncb1975
MeSH Terms: Autophagy/drug effects; Longevity/drug effects; Spermidine/pharmacology
Sources
Ageing-related Data Sources
Additional Data Sources