Ageing Phenotype Observation—Data Type 2 : OB_002729
Last modified: Dec 09, 2014. Release 1 • Page created: Jun 02, 2024
Summary
Species | : | Caenorhabditis elegans | ||||||||||||||
Strain | : | N2 | ||||||||||||||
Gene | : |
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Compound | : | |||||||||||||||
Other Ageing Factor | : |
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Significant Lifespan Effect | : | increased | ||||||||||||||
Change | : | 20.23% | ||||||||||||||
Observed Lifespan | : | 20.8 | ||||||||||||||
Reference Lifespan | : | 17.3 | ||||||||||||||
Lifespan Unit | : | days | ||||||||||||||
Measure | : | mean | ||||||||||||||
Temperature | : | 20 | ||||||||||||||
Temperature Unit | : | ℃ | ||||||||||||||
Sex/Mating Type | : | hermaphrodite | ||||||||||||||
Description | : | Overexpression of DRR-2 has little effect on wild type life span but blunts life span extension from inhibition of TOR or from DR. | ||||||||||||||
Source | : | Lifespan Observations Database (ID: 4023) | ||||||||||||||
Observation Stable ID | : | OB_002729 | ||||||||||||||
Download | : | XML |
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Ching TT, Paal AB, Mehta A, Zhong L, Hsu AL:
drr-2 encodes an eIF4H that acts downstream of TOR in diet-restriction-induced longevity of C. elegans.
Aging Cell. 2010; 9: 545-57.
PubMed (ID: 20456299), PubMed Central (ID: PMC2910166), doi:10.1111/j.1474-9726.2010.00580.x
MeSH Terms: Caenorhabditis elegans Proteins/metabolism; Caenorhabditis elegans/physiology; Caloric Restriction; Diet; Eukaryotic Initiation Factors/metabolism; Longevity/physiology; Phosphotransferases (Alcohol Group Acceptor)/metabolism