Ageing Phenotype Observation—Data Type 2 : OB_002805
Last modified: Dec 09, 2014. Release 1 • Page created: Jun 02, 2024
Summary
Species | : | Mus musculus | ||||||||||||||
Strain | : | |||||||||||||||
Gene | : |
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Compound | : | |||||||||||||||
Other Ageing Factor | : | |||||||||||||||
Significant Lifespan Effect | : | none | ||||||||||||||
Change | : | |||||||||||||||
Observed Lifespan | : | |||||||||||||||
Reference Lifespan | : | |||||||||||||||
Lifespan Unit | : | |||||||||||||||
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Sex/Mating Type | : | female | ||||||||||||||
Description | : | There was no significant difference between females. Knockout decreased lifespan of males by 13% Other phenotypes: Knockout males exhibited premature death and age-related cardiac dysfunction | ||||||||||||||
Observation Stable ID | : | OB_002805 | ||||||||||||||
Source | : | Lifespan Observations Database (ID: 4095) | ||||||||||||||
Download | : | XML |
References
MeSH Terms: Only a subset of the Medical Subject Headings terms is shown: the Major Topics MeSH terms. They describe one of the main topics discussed in the article denoted by an asterisk on the MeSH term or MeSH/Subheading combination on the PubMed page. MeSH terms that belong to the Ageing MeSH are highlighted in green.
- Li W, Mital S, Ojaimi C, Csiszar A, Kaley G, Hintze TH:
Premature death and age-related cardiac dysfunction in male eNOS-knockout mice.
J Mol Cell Cardiol. 2004; 37: 671-80.
PubMed (ID: 15350840), doi:10.1016/j.yjmcc.2004.05.005
MeSH Terms: Aging/pathology; Cardiomegaly/pathology; Nitric Oxide/genetics; Ventricular Dysfunction, Left/mortality; Ventricular Dysfunction, Left/pathology